Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | SOAT1 | P35610 | 3/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | PON1 | P27169 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TYR | P14679 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11252301 | 0.87 | TSHR (0.33) | POLBSOAT1TSHRLMNATYR | |
| SCHEMBL11242387 | 0.83 | SLC6A3 (0.34) | SOAT1 | |
| SCHEMBL11243234 | 0.81 | SOAT1 (0.33) | SOAT1 | |
| SCHEMBL11254777 | 0.81 | SIGMAR1 (0.32) | NPC1RAB9ASMN1; SMN2SIGMAR1 | |
| SCHEMBL11239752 | 0.80 | SOAT1 (0.44) | SOAT1 | |
| SCHEMBL11233432 | 0.79 | NPC1 (0.40) | POLBTSHRPON1LMNATYR | |
| SCHEMBL11236878 | 0.77 | SOAT1 (0.37) | SOAT1MEN1CYP2C19KMT2ANPC1 | |
| SCHEMBL11237330 | 0.76 | KCNH2 (0.41) | TSHRMEN1KMT2APON1NPC1 | |
| SCHEMBL11242322 | 0.75 | ICMT (0.35) | POLBLMNANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL11234440 | 0.73 | MEN1 (0.39) | SOAT1TSHRMEN1CYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4321272-A | Derivatives of substituted N-alkylimidazoles | SYNTEX (U.S.A.) INC. (US) | 1982-03-23 | — | — | US | disclosed |