Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | NAAA | Q02083 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
| ▸ | TLR7 | Q9NYK1 | 6/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11246827 | 0.88 | HPGD (0.46) | HPGDNAAANAMPTALDH1A1FAAH | |
| SCHEMBL11245458 | 0.88 | ALDH1A1 (0.57) | HPGDTLR7MAPTALDH1A1MAPK1 | |
| SCHEMBL11487844 | 0.83 | LMNA (0.47) | HPGDNAAAALDH1A1MAPK1MEN1 | |
| SCHEMBL11240923 | 0.80 | PAM (0.51) | TLR7MAPTALDH1A1 | |
| SCHEMBL11491096 | 0.79 | ALDH1A1 (0.47) | HPGDALDH1A1MAPK1FAAHMEN1 | |
| SCHEMBL11479562 | 0.79 | ALDH1A1 (0.47) | HPGDALDH1A1MAPK1FAAHMEN1 | |
| SCHEMBL11477434 | 0.79 | ALDH1A1 (0.47) | HPGDALDH1A1MAPK1FAAHMEN1 | |
| Bromide SCHEMBL11476767 | 0.78 | ALDH1A1 (0.46) | HPGDALDH1A1MAPK1FAAHMEN1 | |
| Bromide SCHEMBL11482043 | 0.78 | ALDH1A1 (0.46) | HPGDALDH1A1MAPK1FAAHMEN1 | |
| SCHEMBL5458743 | 0.78 | MAPT (0.60) | HPGDTLR7MAPTALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4348399-A | Antiatherosclerotic and hypolipidemic 4-(monoalkylamino)phenyl alkane, alkene and alkyne carbinols, aldehydes, carboxylic acids and derivatives | AMERICAN CYANAMID COMPANY (US) | 1982-09-07 | — | — | US | disclosed |