Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 1/20 | 0.38 |
| ▸ | AURKA | O14965 | 1/20 | 0.36 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | KAT6A | Q92794 | 2/20 | 0.35 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | SLC22A12 | Q96S37 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.33 |
| ▸ | COMT | P21964 | 1/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.33 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fluoride SCHEMBL11240128 | 0.81 | TTR (0.53) | TTRAURKAAURKBCYP1A2KAT6A | |
| Hydrochloric Acid SCHEMBL11248867 | 0.81 | TTR (0.53) | TTRAURKAAURKBCYP1A2SLC9A1 | |
| SCHEMBL3188983 | 0.81 | MEN1 (0.43) | TTRKAT6AMEN1KMT2ASLC22A12 | |
| SCHEMBL11245617 | 0.72 | TAS2R14 (0.42) | KAT6AMEN1KMT2AKDM4ENR1H2 | |
| SCHEMBL12473229 | 0.72 | AXL (0.47) | SLC9A1MEN1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL12310598 | 0.72 | AXL (0.47) | SLC9A1MEN1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL247640 | 0.71 | KMT2A (0.56) | KAT6AMEN1KMT2ASLC22A12HSD11B1 | |
| SCHEMBL29624178 | 0.71 | KMT2A (0.56) | KAT6AMEN1KMT2ASLC22A12HSD11B1 | |
| SCHEMBL795355 | 0.70 | MEN1 (0.41) | CYP1A2KAT6ASLC9A1MEN1KMT2A | |
| SCHEMBL777931 | 0.70 | CA2 (0.48) | TTRCYP1A2MEN1KMT2ASLC22A12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4331613-A | Process for the preparation of trifluoromethylnaphthalenes | BAYER AKTIENGESELLSCHAFT (DE) | 1982-05-25 | — | — | US | disclosed |