Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 8/20 | 0.49 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | CASR | P41180 | 1/20 | 0.41 |
| ▸ | MERTK | Q12866 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | CTSS | P25774 | 1/20 | 0.39 |
| ▸ | GCGR | P47871 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11230532 | 0.88 | MAPT (0.46) | CTSKMAPTPPARGALDH1A1 | |
| SCHEMBL11233874 | 0.86 | SLC6A4 (0.39) | CTSKGAAMAPTPPARGALDH1A1 | |
| SCHEMBL11237796 | 0.86 | GAA (0.43) | GAAMAPTPPARGCASRALDH1A1 | |
| SCHEMBL11230725 | 0.81 | MAPT (0.48) | GAAMAPTALDH1A1NPC1RAB9A | |
| SCHEMBL11237839 | 0.80 | MAPT (0.40) | GAAMAPTCASRALDH1A1 | |
| Hydrochloric Acid SCHEMBL6320326 | 0.80 | SLC6A2 (0.41) | MAPTPPARGCASRALDH1A1 | |
| Hydrochloric Acid SCHEMBL11236943 | 0.79 | MAPT (0.39) | GAAMAPTCASRALDH1A1 | |
| SCHEMBL11234640 | 0.79 | MEN1 (0.46) | MAPTPPARGALDH1A1NPC1RAB9A | |
| SCHEMBL11244735 | 0.78 | TSHR (0.36) | GAAPPARGDRD2DRD4DRD3 | |
| Hydrochloric Acid SCHEMBL11237752 | 0.77 | TSHR (0.36) | GAAPPARGDRD2DRD4DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4356322-A | ADRENERGIC STIMULANTS; CARDIOTONIC AGENTS | VEB ARZNEIMITTELWERK DRESDEN (DD) | 1982-10-26 | — | — | US | claimed |
| US-4356322-A | ADRENERGIC STIMULANTS; CARDIOTONIC AGENTS | VEB ARZNEIMITTELWERK DRESDEN (DD) | 1982-10-26 | — | — | US | disclosed |