Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.38 |
| ▸ | ICMT | O60725 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11237839 | 0.89 | MAPT (0.40) | MEN1KMT2AATMALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL11236943 | 0.88 | MAPT (0.39) | MEN1KMT2AATMALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL11230532 | 0.87 | MAPT (0.46) | SLC6A4ALDH1A1HTTL3MBTL1PPARG | |
| SCHEMBL11246095 | 0.82 | RAB9A (0.46) | MEN1KMT2AATMALDH1A1ICMT | |
| SCHEMBL11230239 | 0.82 | ALDH1A1 (0.46) | MEN1KMT2AALDH1A1L3MBTL1ABCG2 | |
| Hydrochloric Acid SCHEMBL11247369 | 0.81 | ALDH1A1 (0.45) | MEN1KMT2AALDH1A1L3MBTL1ABCG2 | |
| SCHEMBL11237796 | 0.80 | GAA (0.43) | MEN1KMT2ASLC6A4ALDH1A1HTT | |
| SCHEMBL11233874 | 0.80 | SLC6A4 (0.39) | MEN1KMT2ASLC6A4ALDH1A1KDM4E | |
| SCHEMBL11240133 | 0.79 | CTSK (0.49) | ALDH1A1PPARGMAPTNPC1RAB9A | |
| SCHEMBL11244735 | 0.77 | TSHR (0.36) | KMT2ASLC6A4PPARGPPARALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4356322-A | ADRENERGIC STIMULANTS; CARDIOTONIC AGENTS | VEB ARZNEIMITTELWERK DRESDEN (DD) | 1982-10-26 | — | — | US | claimed |
| US-4356322-A | ADRENERGIC STIMULANTS; CARDIOTONIC AGENTS | VEB ARZNEIMITTELWERK DRESDEN (DD) | 1982-10-26 | — | — | US | disclosed |