Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 2/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.35 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 2/20 | 0.33 |
| ▸ | MAOB | P27338 | 2/20 | 0.33 |
| ▸ | LDHA | P00338 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11230532 | 0.89 | MAPT (0.46) | SLC6A4ALDH1A1MAPTHTTCTSK | |
| SCHEMBL11237796 | 0.87 | GAA (0.43) | SLC6A4ALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL11240133 | 0.86 | CTSK (0.49) | ALDH1A1MAPTNPC1RAB9AGAA | |
| SCHEMBL11230725 | 0.82 | MAPT (0.48) | ALDH1A1MAPTKMT2AMEN1NPC1 | |
| SCHEMBL11237839 | 0.81 | MAPT (0.40) | ALDH1A1MAPTKMT2AMEN1GAA | |
| SCHEMBL11234640 | 0.80 | MEN1 (0.46) | SLC6A4ALDH1A1MAPTKMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL11236943 | 0.80 | MAPT (0.39) | ALDH1A1MAPTKMT2AMEN1GAA | |
| SCHEMBL11244735 | 0.76 | TSHR (0.36) | SLC6A4KMT2AGAAMAPK1PPARG | |
| SCHEMBL11231203 | 0.76 | NPC1 (0.38) | ALDH1A1MAPTKMT2AMEN1NPC1 | |
| SCHEMBL11239338 | 0.76 | DRD3 (0.33) | SLC6A4ALDH1A1MAPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4356322-A | ADRENERGIC STIMULANTS; CARDIOTONIC AGENTS | VEB ARZNEIMITTELWERK DRESDEN (DD) | 1982-10-26 | — | — | US | claimed |
| US-4356322-A | ADRENERGIC STIMULANTS; CARDIOTONIC AGENTS | VEB ARZNEIMITTELWERK DRESDEN (DD) | 1982-10-26 | — | — | US | disclosed |