Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 6/20 | 0.39 |
| ▸ | PPARA | Q07869 | 6/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.36 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.36 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.36 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.36 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.36 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | CASR | P41180 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11230532 | 0.89 | MAPT (0.46) | SLC6A4PPARGPPARAMAPTALDH1A1 | |
| SCHEMBL11233874 | 0.87 | SLC6A4 (0.39) | GAASLC6A4PPARGPPARAMAPT | |
| SCHEMBL11240133 | 0.86 | CTSK (0.49) | GAAPPARGMAPTALDH1A1DRD2 | |
| SCHEMBL11238357 | 0.84 | NPC1 (0.43) | GAASLC6A4MAPTALDH1A1MEN1 | |
| Hydrochloric Acid SCHEMBL11233901 | 0.83 | NPC1 (0.43) | GAASLC6A4MAPTALDH1A1MEN1 | |
| SCHEMBL11242830 | 0.82 | TRPV4 (0.35) | SLC6A4PPARGPPARAMAPTALDH1A1 | |
| SCHEMBL11230725 | 0.82 | MAPT (0.48) | GAAMAPTALDH1A1DRD2DRD4 | |
| SCHEMBL11239338 | 0.82 | DRD3 (0.33) | SLC6A4PPARGPPARAMAPTALDH1A1 | |
| SCHEMBL11231203 | 0.82 | NPC1 (0.38) | MAPTALDH1A1DRD2DRD4DRD3 | |
| Hydrochloric Acid SCHEMBL11235609 | 0.81 | DRD3 (0.33) | SLC6A4PPARGPPARAMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4356322-A | ADRENERGIC STIMULANTS; CARDIOTONIC AGENTS | VEB ARZNEIMITTELWERK DRESDEN (DD) | 1982-10-26 | — | — | US | claimed |
| US-4356322-A | ADRENERGIC STIMULANTS; CARDIOTONIC AGENTS | VEB ARZNEIMITTELWERK DRESDEN (DD) | 1982-10-26 | — | — | US | disclosed |