Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.42 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.42 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.42 |
| ▸ | CHRNA5 | P30532 | 2/20 | 0.42 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.40 |
| ▸ | POLR1A | O95602 | 1/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8049484 | 0.93 | MTNR1A (0.47) | OPRM1ALDH1A1L3MBTL1CHRNB2CHRNA7 | |
| SCHEMBL29358366 | 0.87 | CHRNB2 (0.44) | OPRM1ALDH1A1L3MBTL1CHRNB2CHRNA7 | |
| SCHEMBL12506716 | 0.87 | FAP (0.44) | OPRM1ALDH1A1L3MBTL1CHRNB2CHRNA7 | |
| SCHEMBL8320704 | 0.87 | FAP (0.44) | OPRM1ALDH1A1L3MBTL1CHRNB2CHRNA7 | |
| SCHEMBL8050286 | 0.84 | MTNR1A (0.46) | ALDH1A1L3MBTL1CHRNB2CHRNA7CHRNA4 | |
| SCHEMBL21661030 | 0.84 | MTNR1A (0.46) | ALDH1A1L3MBTL1CHRNB2CHRNA7CHRNA4 | |
| SCHEMBL28645032 | 0.84 | DRD2 (0.43) | ALDH1A1CHRNB2CHRNA7CHRNA4CHRNA5 | |
| SCHEMBL15934293 | 0.84 | MTNR1A (0.46) | ALDH1A1L3MBTL1CHRNB2CHRNA7CHRNA4 | |
| SCHEMBL23866583 | 0.82 | DPP4 (0.48) | OPRM1ALDH1A1L3MBTL1CHRNB2CHRNA7 | |
| SCHEMBL16501770 | 0.82 | PREP (0.48) | OPRM1ALDH1A1L3MBTL1CHRNB2CHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4364867-A | URINARY SYSTEM DISORDERS | SOCIETE D'ETUDES SCIENTIFIQUES ET INDUSTRIELLES DE L'ILE DE FRANCE (FR) | 1982-12-21 | — | — | US | disclosed |
| US-4263316-A | ANTISPASMODIC, FOR URINARY DISORDERS | SOCIETE D'ETUDES SCIENTIFIQUES ET INDUSTRIELLES DE L'ILE DE FRANCE (FR) | 1981-04-21 | — | — | US | disclosed |