Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | MITF | O75030 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | PTGES | O14684 | 3/20 | 0.49 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.45 |
| ▸ | NQO1 | P15559 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11240284 | 0.94 | PTGES (0.57) | NPSR1MAPTLMNATP53NPC1 | |
| SCHEMBL11232062 | 0.88 | NPSR1 (0.55) | NPSR1MAPTLMNATP53NPC1 | |
| SCHEMBL11476250 | 0.86 | MAPT (0.59) | MAPTLMNATP53NPC1PKM | |
| SCHEMBL11475990 | 0.84 | PTGES (0.62) | MAPTLMNATP53NPC1PKM | |
| SCHEMBL11466969 | 0.84 | MAPT (0.54) | MAPTLMNATP53NPC1MITF | |
| SCHEMBL11240864 | 0.82 | NPSR1 (0.64) | NPSR1MAPTLMNATP53NPC1 | |
| SCHEMBL11467226 | 0.80 | NPSR1 (0.47) | NPSR1MAPTLMNANPC1RAB9A | |
| SCHEMBL11485827 | 0.79 | PTGES (0.79) | MAPTLMNATP53RAB9AL3MBTL1 | |
| SCHEMBL13108709 | 0.79 | ALDH1A1 (0.53) | NPSR1MAPTTP53NPC1RAB9A | |
| SCHEMBL11247874 | 0.79 | CACNA2D1 (0.55) | MAPTTP53NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4190725-A | ANTIINFLAMMATORY | ELI LILLY AND COMPANY (US) | 1980-02-26 | — | — | US | disclosed |
| US-4021553-A | 5,6-Diaryl-1,2,4-triazines as topically-active anti-inflammatory agents | ELI LILLY AND COMPANY (US) | 1977-05-03 | — | — | US | disclosed |