Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | SPHK1 | Q9NYA1 | 4/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11276601 | 0.88 | HPGD (0.51) | TRPV1HPGDSPHK1KCNH2 | |
| SCHEMBL11067061 | 0.82 | L3MBTL1 (0.51) | HPGDKCNH2ALDH1A1LMNA | |
| SCHEMBL11237793 | 0.80 | ALDH1A1 (0.61) | TRPV1HPGDEPHX1ALDH1A1LMNA | |
| SCHEMBL11233653 | 0.79 | TRPV1 (0.56) | TRPV1HPGDTLR7 | |
| SCHEMBL11245563 | 0.78 | EGFR (0.54) | ALDH1A1LMNA | |
| SCHEMBL11245566 | 0.78 | EGFR (0.54) | ALDH1A1LMNA | |
| SCHEMBL28309209 | 0.77 | NLRP3 (0.49) | HPGDALDH1A1 | |
| SCHEMBL22664689 | 0.76 | ALDH1A1 (0.59) | HPGDALDH1A1LMNA | |
| SCHEMBL11227278 | 0.76 | ALDH1A1 (0.60) | HPGDEPHX1ALDH1A1 | |
| SCHEMBL11235833 | 0.76 | ALDH1A1 (0.60) | HPGDEPHX1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4348399-A | Antiatherosclerotic and hypolipidemic 4-(monoalkylamino)phenyl alkane, alkene and alkyne carbinols, aldehydes, carboxylic acids and derivatives | AMERICAN CYANAMID COMPANY (US) | 1982-09-07 | — | — | US | disclosed |