Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | ATM | Q13315 | 2/20 | 0.46 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | CASP1 | P29466 | 2/20 | 0.41 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11235524 | 0.82 | KDM4E (0.56) | KMT2AMEN1ATMALDH1A1CASP1 | |
| SCHEMBL11222288 | 0.82 | MEN1 (0.40) | KMT2AMEN1ATMPABPC1ALDH1A1 | |
| SCHEMBL11236486 | 0.79 | ATM (0.44) | KMT2AMEN1ATMPABPC1ALDH1A1 | |
| SCHEMBL11229128 | 0.71 | KDM4E (0.50) | KMT2AMEN1ATMPABPC1ALDH1A1 | |
| SCHEMBL11233210 | 0.71 | MEN1 (0.43) | KMT2AMEN1ATMPABPC1ALDH1A1 | |
| SCHEMBL11240784 | 0.69 | PDE3B (0.46) | ALDH1A1PDE3BPDE3AKDM4EGAA | |
| SCHEMBL7291097 | 0.68 | SMN1; SMN2 (0.48) | KMT2AALDH1A1PDE3BPDE3AKDM4E | |
| SCHEMBL11233335 | 0.68 | ATM (0.39) | KMT2AMEN1ATMPABPC1ALDH1A1 | |
| SCHEMBL18604300 | 0.68 | PDE3B (0.43) | ALDH1A1PDE3BPDE3AKDM4EGAA | |
| SCHEMBL11237388 | 0.67 | PDE3B (0.44) | ALDH1A1PDE3BPDE3AKDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4361568-A | 5-(Pyridinyl)-1H-pyrazolo[3,4-b]pyridin-3-amines and their cardiotonic use | STERLING DRUG INC. (US) | 1982-11-30 | — | — | US | disclosed |