Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 4/20 | 0.44 |
| ▸ | BCHE | P06276 | 5/20 | 0.44 |
| ▸ | DRD2 | P14416 | 2/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.44 |
| ▸ | DRD3 | P35462 | 2/20 | 0.44 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.38 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.38 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6405794 | 0.88 | TSHR (0.47) | BCHEDRD2OPRM1DRD3OPRD1 | |
| SCHEMBL7130458 | 0.84 | KCNH2 (0.54) | KCNH2BCHEDRD2OPRM1DRD3 | |
| SCHEMBL6406763 | 0.81 | ACHE (0.47) | BCHE | |
| SCHEMBL1881521 | 0.80 | LPL (0.53) | — | |
| SCHEMBL11440647 | 0.80 | LPL (0.53) | — | |
| SCHEMBL7536683 | 0.80 | LPL (0.53) | — | |
| SCHEMBL5147572 | 0.80 | LPL (0.53) | — | |
| SCHEMBL4083034 | 0.80 | LPL (0.53) | — | |
| SCHEMBL609813 | 0.79 | BCHE (0.49) | KCNH2BCHEDRD2OPRM1DRD3 | |
| SCHEMBL7766004 | 0.78 | KCNH2 (0.60) | KCNH2BCHEDRD2OPRM1DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0013592-B1 | N,N-DISUBSTITUTED-AMINOMETHYL-PHENYLETHANOLAMINES AND PHARMACEUTICAL FORMULATIONS THEREOF | PFIZER INC. (US) | 1982-12-15 | — | — | EP | disclosed |
| EP-0013592-A1 | N,N-disubstituted-aminomethyl-phenylethanolamines and pharmaceutical formulations thereof | PFIZER INC. (US) | 1980-07-23 | — | — | EP | disclosed |
| US-4211794-A | ANTIVIRAL INTERFERON PRODUCTION | PFIZER INC. (US) | 1980-07-08 | — | — | US | disclosed |