SCHEMBL6405794

SCHEMBL6405794

CCCN(CCC)Cc1cccc(C=O)c1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.47
HSD17B10 Q99714 1/20 0.47
BCHE P06276 4/20 0.46
HRH3 Q9Y5N1 1/20 0.46
ALDH3A1 P30838 3/20 0.43
ALDH1A3 P47895 2/20 0.43
ALDH1A1 P00352 2/20 0.43
DRD2 P14416 2/20 0.41
DRD3 P35462 2/20 0.41
DRD1 P21728 1/20 0.41
DRD4 P21917 1/20 0.41
DRD5 P21918 1/20 0.41
MAOA P21397 3/20 0.41
MAOB P27338 3/20 0.41
GRIN2D O15399 1/20 0.40
GRIN3B O60391 1/20 0.40
GRIN1 Q05586 1/20 0.40
GRIN2A Q12879 1/20 0.40
GRIN2B Q13224 1/20 0.40
GRIN2C Q14957 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11240427 0.88 KCNH2 (0.44) BCHEDRD2DRD3OPRM1OPRD1
SCHEMBL6406763 0.86 ACHE (0.47) BCHEHRH3ALDH3A1ALDH1A3ALDH1A1
SCHEMBL13280625 0.85 ALDH3A1 (0.42) BCHEALDH3A1ALDH1A3ALDH1A1MAOA
SCHEMBL608707 0.83 TSHR (0.47) TSHRHSD17B10BCHEHRH3ALDH1A1
SCHEMBL20462967 0.81 TSHR (0.48) TSHRHSD17B10BCHEHRH3DRD2
SCHEMBL5778962 0.79 ALDH1A1 (0.48) TSHRHRH3ALDH1A1MAOAMAOB
SCHEMBL1206075 0.79 HRH3 (0.62) HRH3ALDH3A1ALDH1A3ALDH1A1
SCHEMBL8577448 0.78 TSHR (0.43) TSHRHSD17B10BCHEHRH3ALDH1A1
SCHEMBL14732594 0.78 BCHE (0.42) TSHRHSD17B10BCHEHRH3DRD2
SCHEMBL15650774 0.78 MAOA (0.39) ALDH3A1ALDH1A3ALDH1A1MAOAMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050222098-A1 Regulation of meiosis NOVO NORDISK A/S (DK) 2005-10-06 US disclosed
EP-0767798-B1 STEROL DERIVATIVES USED FOR REGULATION OF MEIOSIS NOVO NORDISK AS (DK) 2003-09-03 EP disclosed
US-20030004148-A1 Regulation of meiosis NOVO NORDISK A/S (DK) 2003-01-02 US disclosed
EP-0767798-A1 STEROL DERIVATIVES USED FOR REGULATION OF MEIOSIS NOVO NORDISK A/S (DK) 1997-04-16 EP disclosed
WO-1996000235-A1 STEROL DERIVATIVES USED FOR REGULATION OF MEIOSIS NOVO NORDISK A/S (DK) 1996-01-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050222098-A1 Regulation of meiosis ALPG, MNS1, BUB1B TSHR 4376/4885HSD17B10 1314/4885BCHE 3553/4885
US-20030004148-A1 Regulation of meiosis ALPG, MNS1, BUB1B TSHR 4376/4885HSD17B10 1314/4885BCHE 3553/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.