Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | S100A4 | P26447 | 1/20 | 0.34 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.34 |
| ▸ | KCNMA1 | Q12791 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | FBP1 | P09467 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CTSB | P07858 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TSPO | P30536 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6825300 | 0.76 | ATM (0.42) | MEN1KMT2AMAPTALDH1A1L3MBTL1 | |
| SCHEMBL11148838 | 0.75 | ALDH1A1 (0.35) | GAAMEN1KMT2AMAPTGPR35 | |
| SCHEMBL5083037 | 0.75 | GPR35 (0.39) | GAAMEN1KMT2AMAPTS100A4 | |
| SCHEMBL11565235 | 0.74 | GAA (0.61) | GAAMEN1KMT2AMAPTTHRB | |
| SCHEMBL5373508 | 0.73 | GPR35 (0.38) | GAAMEN1KMT2AMAPTS100A4 | |
| SCHEMBL5536970 | 0.72 | TSPO (0.55) | GAAMAPTTHRBALDH1A1TDP1 | |
| SCHEMBL7616291 | 0.72 | GPR35 (0.37) | GAAMEN1KMT2AMAPTS100A4 | |
| SCHEMBL14956444 | 0.70 | ESR1 (0.37) | GAAMEN1KMT2AMAPTTHRB | |
| SCHEMBL5738106 | 0.69 | GAA (0.41) | GAAMEN1KMT2AMAPTTHRB | |
| SCHEMBL2522993 | 0.69 | HTR1A (0.40) | TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0011843-B1 | DEVELOPING COMPONENTS FOR HAIR OXYDATION DYES, THEIR PREPARATION AND HAIR DYES CONTAINING THEM | Henkel Kommanditgesellschaft auf Aktien (DE) | 1982-09-15 | — | — | EP | disclosed |
| EP-0011844-B1 | COUPLING COMPONENTS FOR OXIDIZING HAIR DYES, THEIR PREPARATION AND HAIR DYES CONTAINING THEM | Henkel Kommanditgesellschaft auf Aktien (DE) | 1982-05-26 | — | — | EP | disclosed |
| US-4231964-A | Nitroamines, processes for their manufacture and their use as diazo components | HOECHST AKTIENGESELLSCHAFT (DE) | 1980-11-04 | — | — | US | disclosed |
| EP-0011843-A2 | Developing components for hair oxydation dyes, their preparation and hair dyes containing them | Henkel Kommanditgesellschaft auf Aktien (DE) | 1980-06-11 | — | — | EP | disclosed |
| EP-0011844-A1 | Coupling components for oxidizing hair dyes, their preparation and hair dyes containing them | Henkel Kommanditgesellschaft auf Aktien (DE) | 1980-06-11 | — | — | EP | disclosed |