SCHEMBL11240740

SCHEMBL11240740

CC(C)C(=NO)n1cncn1

nearest known ligand 0.35

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.35
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
ALDH1A1 P00352 1/20 0.34
FAAH O00519 1/20 0.32
MGLL Q99685 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11240738 1.00 ATM (0.35) ATMMEN1KMT2AALDH1A1FAAH
SCHEMBL11237997 0.74 MEN1 (0.33) ATMMEN1KMT2AALDH1A1FAAH
SCHEMBL11241299 0.74
SCHEMBL11241293 0.74
SCHEMBL14884967 0.74
SCHEMBL11240793 0.71 ATM (0.33) ATMMEN1KMT2AFAAHMGLL
SCHEMBL26822942 0.71 ATM (0.42) ATMMEN1KMT2AALDH1A1FAAH
SCHEMBL11230869 0.70 RAB9A (0.33) ATMMEN1KMT2AALDH1A1FAAH
SCHEMBL11238546 0.68 RAB9A (0.39) ATMMEN1KMT2AALDH1A1FAAH
SCHEMBL11224887 0.68 NOS1 (0.50)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4359469-A Combating pests with N-sulphenylated oxime-carbamates BAYER AKTIENGESELLSCHAFT (DE) 1982-11-16 US disclosed
EP-0005780-A1 N,N'-asymmetrically substituted thio-bis-amines, process for their preparation and their use as insecticides, acaricides and nematocides BAYER AG (DE) 1979-12-12 EP disclosed