Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | S1PR4 | O95977 | 7/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | XBP1 | P17861 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Maleic Acid SCHEMBL11241428 | 0.89 | KDM4E (0.50) | HPGDNPC1LMNAPKMRAB9A | |
| SCHEMBL11247290 | 0.80 | NPSR1 (0.55) | LMNAKCNH2ALDH1A1SMN1; SMN2 | |
| Maleic Acid SCHEMBL11248410 | 0.80 | KDM4E (0.58) | HPGDNPC1LMNARAB9AKDM4E | |
| SCHEMBL8540415 | 0.77 | HTT (0.53) | HPGDNPC1LMNARAB9AS1PR4 | |
| SCHEMBL11240131 | 0.77 | ALDH1A1 (0.47) | HPGDLMNAKDM4EALDH1A1HTT | |
| SCHEMBL11251413 | 0.76 | KDM4E (0.49) | NPC1LMNAKCNH2KDM4EALDH1A1 | |
| Maleic Acid SCHEMBL11245948 | 0.75 | KDM4E (0.46) | HPGDNPC1LMNAPKMRAB9A | |
| SCHEMBL11151952 | 0.75 | FFAR1 (0.46) | KDM4EALDH1A1HTTSMN1; SMN2GAA | |
| SCHEMBL11145929 | 0.75 | FFAR1 (0.46) | KCNH2KDM4EALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL17482331 | 0.73 | ALDH1A1 (0.76) | LMNAPKMKDM4EALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0049060-A1 | Imidazoles | BEECHAM GROUP PLC (GB) | 1982-04-07 | — | — | EP | claimed |
| EP-0049060-A1 | Imidazoles | BEECHAM GROUP PLC (GB) | 1982-04-07 | — | — | EP | disclosed |