Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Maleic Acid SCHEMBL11263894 | 0.88 | ALDH1A1 (0.43) | ALDH1A1KMT2APOLBHPGDSMN1; SMN2 | |
| SCHEMBL11247290 | 0.84 | NPSR1 (0.55) | ALDH1A1KMT2APOLBMAPTSMN1; SMN2 | |
| SCHEMBL11251413 | 0.81 | KDM4E (0.49) | ALDH1A1KMT2APOLBLMNAKDM4E | |
| SCHEMBL11142733 | 0.78 | TBXAS1 (0.51) | ALDH1A1KMT2APOLBTP53HTT | |
| Maleic Acid SCHEMBL11250986 | 0.77 | MCL1 (0.50) | ALDH1A1KMT2AMAPTTP53GAA | |
| Maleic Acid SCHEMBL11264466 | 0.77 | ALDH1A1 (0.43) | ALDH1A1KMT2APOLBHPGDSMN1; SMN2 | |
| SCHEMBL11248409 | 0.77 | ALDH1A1 (0.54) | ALDH1A1KMT2APOLBTSHRSMN1; SMN2 | |
| SCHEMBL11241447 | 0.77 | HPGD (0.56) | ALDH1A1GAAMAPK1HPGDSMN1; SMN2 | |
| SCHEMBL11243418 | 0.76 | ALDH1A1 (0.53) | ALDH1A1KMT2APOLBSMN1; SMN2HTT | |
| SCHEMBL8678546 | 0.76 | KMT2A (0.60) | ALDH1A1KMT2APOLBHPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0049060-A1 | Imidazoles | BEECHAM GROUP PLC (GB) | 1982-04-07 | — | — | EP | disclosed |