Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT2B | Q92831 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 4/20 | 0.55 |
| ▸ | RAB9A | P51151 | 4/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11230725 | 0.81 | MAPT (0.48) | NPC1RAB9AMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL11231203 | 0.79 | NPC1 (0.38) | NPC1RAB9AMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL11230239 | 0.79 | ALDH1A1 (0.46) | NPC1RAB9AMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL11241745 | 0.78 | MAPT (0.60) | KAT2BNPC1RAB9AMAPTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL11226921 | 0.78 | RAB9A (0.37) | NPC1RAB9AMAPTSMN1; SMN2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL11247369 | 0.78 | ALDH1A1 (0.45) | NPC1RAB9AMAPTSMN1; SMN2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL11230532 | 0.76 | MAPT (0.46) | MAPTSMN1; SMN2ALDH1A1HTT | |
| SCHEMBL9300696 | 0.76 | KAT2B (0.60) | KAT2BNPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL9300700 | 0.76 | KAT2B (0.60) | KAT2BNPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL7170020 | 0.75 | KAT2B (0.81) | KAT2BNPC1RAB9AMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4356322-A | ADRENERGIC STIMULANTS; CARDIOTONIC AGENTS | VEB ARZNEIMITTELWERK DRESDEN (DD) | 1982-10-26 | — | — | US | claimed |
| US-4356322-A | ADRENERGIC STIMULANTS; CARDIOTONIC AGENTS | VEB ARZNEIMITTELWERK DRESDEN (DD) | 1982-10-26 | — | — | US | disclosed |