Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.60 |
| ▸ | NPC1 | O15118 | 5/20 | 0.60 |
| ▸ | RAB9A | P51151 | 5/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.60 |
| ▸ | KAT2B | Q92831 | 2/20 | 0.48 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.45 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.45 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CDK4 | P11802 | 1/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11230723 | 0.82 | MEN1 (0.48) | MAPTADRB2ADRB1ADRB3KMT2A | |
| SCHEMBL11231201 | 0.80 | NPC1 (0.43) | MAPTNPC1RAB9ASMN1; SMN2ADRB2 | |
| SCHEMBL11243705 | 0.80 | TSHR (0.46) | MAPTNPC1RAB9ASMN1; SMN2ADRB2 | |
| SCHEMBL11230236 | 0.79 | ALDH1A1 (0.50) | MAPTSMN1; SMN2ADRB2ADRB1ADRB3 | |
| Hydrochloric Acid SCHEMBL11226919 | 0.79 | ADRB2 (0.42) | MAPTNPC1RAB9ASMN1; SMN2ADRB2 | |
| Hydrochloric Acid SCHEMBL11247363 | 0.78 | ADRB1 (0.50) | MAPTSMN1; SMN2ADRB2ADRB1ADRB3 | |
| SCHEMBL30001137 | 0.78 | ADRB1 (0.62) | MAPTNPC1RAB9ASMN1; SMN2KAT2B | |
| SCHEMBL11241752 | 0.78 | KAT2B (0.55) | MAPTNPC1RAB9ASMN1; SMN2KAT2B | |
| SCHEMBL11241719 | 0.78 | ADRB1 (0.62) | MAPTNPC1RAB9ASMN1; SMN2KAT2B | |
| Hydrochloric Acid SCHEMBL11230529 | 0.76 | MAPT (0.50) | MAPTSMN1; SMN2ADRB2ADRB1ADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4356322-A | ADRENERGIC STIMULANTS; CARDIOTONIC AGENTS | VEB ARZNEIMITTELWERK DRESDEN (DD) | 1982-10-26 | — | — | US | claimed |
| US-4356322-A | ADRENERGIC STIMULANTS; CARDIOTONIC AGENTS | VEB ARZNEIMITTELWERK DRESDEN (DD) | 1982-10-26 | — | — | US | disclosed |