Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 4/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | MITF | O75030 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11245003 | 0.81 | KLK5 (0.34) | NPC1RAB9ASMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL8981523 | 0.81 | TAAR1 (0.42) | TDP1NPC1RAB9ASMN1; SMN2TP53 | |
| SCHEMBL29903162 | 0.76 | TSHR (0.43) | NPC1RAB9ASMN1; SMN2ALDH1A1TAAR1 | |
| SCHEMBL15486522 | 0.73 | MTNR1A (0.48) | SMN1; SMN2TP53ALDH1A1MEN1CYP3A4 | |
| SCHEMBL11246795 | 0.73 | TP53 (0.37) | TDP1NPC1RAB9ASMN1; SMN2TP53 | |
| SCHEMBL17656432 | 0.73 | ALDH1A1 (0.42) | SMN1; SMN2TP53ALDH1A1TAAR1MEN1 | |
| SCHEMBL175818 | 0.71 | NPC1 (0.56) | TDP1NPC1RAB9ASMN1; SMN2ALDH1A1 | |
| Water SCHEMBL44278 | 0.71 | TAAR1 (0.36) | NPC1RAB9ASMN1; SMN2ATMTP53 | |
| SCHEMBL10718163 | 0.71 | ALDH1A1 (0.66) | TDP1RAB9ASMN1; SMN2TP53ALDH1A1 | |
| SCHEMBL8577301 | 0.70 | TDP1 (0.49) | TDP1NPC1RAB9ASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4323662-A | Thermosetting resin compositions comprising bismaleimides and alkenylaniline derivatives | MITSUI TOATSU CHEMICALS, INC. (JP) | 1982-04-06 | — | — | US | disclosed |