Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.33 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.31 |
| ▸ | NAMPT | P43490 | 3/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8981580 | 0.82 | SMN1; SMN2 (0.42) | KLK5SMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL11241763 | 0.81 | TDP1 (0.38) | SMN1; SMN2NPC1RAB9AALDH1A1MAPT | |
| SCHEMBL244947 | 0.80 | MAPT (0.50) | SMN1; SMN2NPC1RAB9AALDH1A1MAPT | |
| SCHEMBL4271408 | 0.77 | L3MBTL1 (0.41) | SMN1; SMN2NPC1RAB9AALDH1A1MAPT | |
| SCHEMBL21401818 | 0.76 | SMN1; SMN2 (0.39) | KLK5SMN1; SMN2NPC1RAB9AALDH1A1 | |
| Water SCHEMBL28325020 | 0.75 | L3MBTL1 (0.40) | SMN1; SMN2NPC1RAB9AALDH1A1MAPT | |
| SCHEMBL9064071 | 0.74 | ALDH1A1 (0.33) | ALDH1A1KMT2A | |
| SCHEMBL10734594 | 0.73 | NPC1 (0.44) | SMN1; SMN2NPC1RAB9AALDH1A1MAPT | |
| SCHEMBL7535852 | 0.73 | LMNA (0.38) | SMN1; SMN2NPC1RAB9AALDH1A1KMT2A | |
| SCHEMBL11702489 | 0.73 | RAB9A (0.37) | KLK5SMN1; SMN2NPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4323662-A | Thermosetting resin compositions comprising bismaleimides and alkenylaniline derivatives | MITSUI TOATSU CHEMICALS, INC. (JP) | 1982-04-06 | — | — | US | disclosed |