Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.62 |
| ▸ | MAPT | P10636 | 2/20 | 0.62 |
| ▸ | POLB | P06746 | 2/20 | 0.59 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.58 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.56 |
| ▸ | MMP2 | P08253 | 4/20 | 0.56 |
| ▸ | MMP9 | P14780 | 4/20 | 0.56 |
| ▸ | MMP1 | P03956 | 2/20 | 0.56 |
| ▸ | MMP8 | P22894 | 2/20 | 0.56 |
| ▸ | CA1 | P00915 | 2/20 | 0.56 |
| ▸ | CA2 | P00918 | 2/20 | 0.56 |
| ▸ | MMP13 | P45452 | 1/20 | 0.56 |
| ▸ | IDO1 | P14902 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | CRHBP | P24387 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.55 |
| ▸ | MMP3 | P08254 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7908701 | 0.91 | POLB (0.68) | LMNAMAPTPOLBADAMTS4MMP2 | |
| SCHEMBL11242568 | 0.84 | LMNA (0.69) | LMNAMAPTPOLBPLA2G7MMP2 | |
| SCHEMBL10536063 | 0.82 | PKM (0.70) | LMNAMAPTPLA2G7MMP2MMP9 | |
| SCHEMBL9815431 | 0.82 | PKM (0.70) | LMNAMAPTPLA2G7MMP2MMP9 | |
| SCHEMBL11239362 | 0.80 | MMP2 (0.60) | PLA2G7MMP2MMP9MMP1MMP8 | |
| SCHEMBL11249713 | 0.80 | POLB (0.66) | LMNAMAPTPOLBPLA2G7MMP2 | |
| SCHEMBL24200403 | 0.80 | KMT2A (0.59) | LMNAMAPTPOLBCA1CA2 | |
| SCHEMBL6516221 | 0.79 | KMT2A (0.73) | LMNAMAPTPOLBCA1CA2 | |
| SCHEMBL31500692 | 0.79 | MMP2 (0.59) | LMNAMAPTPOLBPLA2G7MMP2 | |
| SCHEMBL16000119 | 0.79 | MMP9 (0.68) | LMNAMAPTPOLBADAMTS4MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4337274-A | Flukicidal compounds | BURROUGHS WELLCOME CO. (US) | 1982-06-29 | — | — | US | claimed |
| US-4337274-A | Flukicidal compounds | BURROUGHS WELLCOME CO. (US) | 1982-06-29 | — | — | US | disclosed |