Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 2/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 7/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7693974 | 0.92 | SLC6A3 (0.60) | DHODHSLC6A3NPSR1SLC6A2NPC1 | |
| SCHEMBL10843167 | 0.84 | MEN1 (0.58) | SLC6A3NPSR1SLC6A2SMN1; SMN2MAPT | |
| SCHEMBL2131145 | 0.80 | SLC6A3 (0.53) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL8636289 | 0.76 | SLC6A3 (0.53) | SLC6A3NPSR1SLC6A2SLC6A4 | |
| SCHEMBL8762690 | 0.73 | DHODH (0.76) | DHODHNPSR1SMN1; SMN2 | |
| SCHEMBL2371417 | 0.72 | SLC6A3 (0.54) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL3914856 | 0.72 | DHODH (0.69) | DHODHNPSR1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL3924512 | 0.72 | DHODH (0.72) | DHODHSLC6A3NPC1RAB9ATP53 | |
| SCHEMBL3915685 | 0.72 | DHODH (0.60) | DHODHNPC1RAB9ATP53SMN1; SMN2 | |
| SCHEMBL11241892 | 0.71 | TSHR (0.53) | DHODHNPSR1NPC1RAB9ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180126784-A1 | RUBBER COMPOSITION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2018-05-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180126784-A1 | RUBBER COMPOSITION | RER1, KPNB1, KPNA1 | DHODH 2822/4885SLC6A3 4880/4885NPSR1 3042/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.