Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | CRHBP | P24387 | 1/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11681681 | 0.78 | KDM4E (0.42) | HPGDRAB9ANPC1CRHBPCRHR2 | |
| SCHEMBL3804394 | 0.76 | KDM4E (0.45) | HPGDRAB9ANPC1CRHBPCRHR2 | |
| SCHEMBL11767621 | 0.68 | KDM4E (0.70) | HPGDRAB9ANPC1CRHBPCRHR2 | |
| SCHEMBL10740240 | 0.67 | CYP1A2 (0.49) | HPGDRAB9ANPC1CRHBPCRHR2 | |
| SCHEMBL3443278 | 0.66 | KMT2A (0.44) | HPGDRAB9ANPC1CRHBPCRHR2 | |
| SCHEMBL28401182 | 0.65 | ALDH1A1 (0.72) | HPGDRAB9ANPC1CRHBPCRHR2 | |
| SCHEMBL7565510 | 0.64 | RAB9A (0.71) | HPGDRAB9ANPC1CRHBPCRHR2 | |
| SCHEMBL9689335 | 0.64 | CYP1A2 (0.48) | HPGDRAB9ANPC1CRHBPCRHR2 | |
| SCHEMBL9146676 | 0.64 | LMNA (0.68) | HPGDRAB9ANPC1CRHBPCRHR2 | |
| SCHEMBL10791960 | 0.64 | KDM4E (0.64) | HPGDRAB9ANPC1CRHBPCRHR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4361516-A | N-Monosubstituted indoanilines | SOCIETE ANONYME DITE: L'OREAL (FR) | 1982-11-30 | — | — | US | disclosed |
| US-4008043-A | Diphenylamines for dyeing keratinic fibers | L'OREAL (FR) | 1977-02-15 | — | — | US | disclosed |