Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | GSK3A | P49840 | 2/20 | 0.37 |
| ▸ | GSK3B | P49841 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11232126 | 0.98 | KDM4E (0.37) | ALDH1A1KDM4ESMN1; SMN2MAPTMEN1 | |
| SCHEMBL11242383 | 0.93 | GSK3A (0.38) | ALDH1A1KDM4ESMN1; SMN2MEN1KMT2A | |
| SCHEMBL11247969 | 0.88 | SMN1; SMN2 (0.39) | ALDH1A1KDM4ESMN1; SMN2MAPTNPC1 | |
| SCHEMBL11237223 | 0.88 | MAPT (0.35) | ALDH1A1KDM4ESMN1; SMN2MAPTMEN1 | |
| SCHEMBL11235510 | 0.87 | RORA (0.36) | MEN1KMT2ATDP1GSK3AGSK3B | |
| SCHEMBL11063319 | 0.86 | ALDH1A1 (0.36) | ALDH1A1KDM4ESMN1; SMN2MAPTMEN1 | |
| SCHEMBL29044637 | 0.86 | GSK3A (0.40) | ALDH1A1KDM4ESMN1; SMN2MEN1KMT2A | |
| SCHEMBL11071245 | 0.85 | ALDH1A1 (0.35) | ALDH1A1KDM4ESMN1; SMN2MAPTMEN1 | |
| SCHEMBL11232140 | 0.82 | LYN (0.36) | ALDH1A1KDM4ESMN1; SMN2MAPTMEN1 | |
| SCHEMBL11236537 | 0.81 | GSK3A (0.39) | ALDH1A1KDM4ESMN1; SMN2MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4337340-A | FROM DIPHENYLAMINES AND BENZOYL OR 3-INDOLYLCARBONYL PYRIDINE- OR PYRAZINECARBOXYLIC ACIDS | STERLING DRUG INC. (US) | 1982-06-29 | — | — | US | disclosed |
| US-4243250-A | FUROPYRIDINONES OR FUROPYRAZINONES AS COLOR FORMERS | STERLING DRUG INC. (US) | 1981-01-06 | — | — | US | disclosed |
| US-4211872-A | COLOR FORMERS | FREEDOM CHEMICAL COMPANY | 1980-07-08 | — | — | US | disclosed |