Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.33 |
| ▸ | METAP2 | P50579 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 3/20 | 0.32 |
| ▸ | PPARA | Q07869 | 3/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | DRD4 | P21917 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11239338 | 0.90 | DRD3 (0.33) | NPC1RAB9ASLC6A4METAP2HSP90AA1 | |
| Hydrochloric Acid SCHEMBL11235609 | 0.89 | DRD3 (0.33) | NPC1RAB9ASLC6A4METAP2HSP90AA1 | |
| SCHEMBL11238357 | 0.86 | NPC1 (0.43) | TRPV4NPC1RAB9AL3MBTL1SLC6A4 | |
| Hydrochloric Acid SCHEMBL11233901 | 0.85 | NPC1 (0.43) | TRPV4NPC1RAB9AL3MBTL1SLC6A4 | |
| SCHEMBL11231203 | 0.82 | NPC1 (0.38) | NPC1RAB9AHSP90AA1HSP90AB1MEN1 | |
| SCHEMBL11237796 | 0.82 | GAA (0.43) | SLC6A4MEN1KMT2AALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL11226921 | 0.81 | RAB9A (0.37) | NPC1RAB9AHSP90AA1HSP90AB1MEN1 | |
| SCHEMBL11244735 | 0.80 | TSHR (0.36) | SLC6A4KMT2APPARGPPARADRD2 | |
| Hydrochloric Acid SCHEMBL11230532 | 0.79 | MAPT (0.46) | L3MBTL1SLC6A4ALDH1A1MAPTPPARG | |
| Hydrochloric Acid SCHEMBL11237752 | 0.79 | TSHR (0.36) | SLC6A4KMT2APPARGPPARADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4356322-A | ADRENERGIC STIMULANTS; CARDIOTONIC AGENTS | VEB ARZNEIMITTELWERK DRESDEN (DD) | 1982-10-26 | — | — | US | claimed |
| US-4356322-A | ADRENERGIC STIMULANTS; CARDIOTONIC AGENTS | VEB ARZNEIMITTELWERK DRESDEN (DD) | 1982-10-26 | — | — | US | disclosed |