Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 2/20 | 0.51 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | ABL1 | P00519 | 1/20 | 0.48 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.48 |
| ▸ | BCR | P11274 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.47 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12687096 | 0.86 | CYP1A1 (0.55) | ALDH1A1ABL1ABCB1BCRRAB9A | |
| SCHEMBL12736515 | 0.86 | GSTP1 (0.47) | BACE1KDM4EHPGDSMN1; SMN2KMT2A | |
| SCHEMBL17548649 | 0.85 | ALKBH3 (0.50) | BACE1ABL1ABCB1BCRCYP1A2 | |
| SCHEMBL17054243 | 0.84 | ACHE (0.54) | KDM4EALDH1A1HPGDSMN1; SMN2ABL1 | |
| SCHEMBL7822185 | 0.84 | ESR2 (0.55) | BACE1PIN1PTPN1KDM4EALDH1A1 | |
| SCHEMBL12325013 | 0.83 | PTPN1 (0.57) | BACE1PIN1PTPN1KDM4EALDH1A1 | |
| SCHEMBL29402037 | 0.83 | PTPN1 (0.57) | BACE1PIN1PTPN1KDM4EALDH1A1 | |
| SCHEMBL5551697 | 0.83 | PTPN1 (0.57) | BACE1PIN1PTPN1KDM4EALDH1A1 | |
| SCHEMBL21480791 | 0.82 | CYP1A2 (0.48) | KDM4EALDH1A1SMN1; SMN2ABL1ABCB1 | |
| Hydrogen Sulfide SCHEMBL27936907 | 0.82 | PTPN1 (0.56) | BACE1PIN1PTPN1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11858952-B2 | Compound and color conversion film comprising same | LG CHEM, LTD. (KR) | 2024-01-02 | — | — | US | disclosed |
| US-11858952-B2 | Compound and color conversion film comprising same | LG CHEM, LTD. (KR) | 2024-01-02 | — | — | US | disclosed |
| US-20210347790-A1 | COMPOUND AND COLOR CONVERSION FILM COMPRISING SAME | LG CHEM, LTD. (KR) | 2021-11-11 | — | — | US | disclosed |
| EP-3110818-B1 | 9H-PYRIMIDO[4,5-B]INDOLES AND RELATED ANALOGS AS BET BROMODOMAIN INHIBITORS | UNIV MICHIGAN REGENTS (US) | 2019-10-23 | — | — | EP | disclosed |
| US-20170210761-A1 | 9H-PYRIMIDO [4,5-B]INDOLES AND RELATED ANALOGS AS BET BROMODOMAIN INHIBITORS | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2017-07-27 | — | — | US | disclosed |
| US-9580430-B2 | 9H-pyrimido[4,5-B]indoles and related analogs as BET bromodomain inhibitors | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2017-02-28 | — | — | US | disclosed |
| US-20150246923-A1 | 9H-PYRIMIDO[4,5-B]INDOLES AND RELATED ANALOGS AS BET BROMODOMAIN INHIBITORS | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2015-09-03 | — | — | US | disclosed |
| US-8247234-B2 | Isotopically labeled compositions and method | LOS ALAMOS NATIONAL SECURITY, LLC (US) | 2012-08-21 | — | — | US | disclosed |
| US-20110269985-A1 | ISOTOPICALLY LABELED COMPOSITIONS AND METHOD | LOS ALAMOS NATIONAL SECURITY, LLC (US) | 2011-11-03 | — | — | US | disclosed |
| US-7977102-B2 | Isotopically labeled compositions and method | LOS ALAMOS NATIONAL SECURITY, LLC (US) | 2011-07-12 | — | — | US | disclosed |
| US-4318783-A | Process for the preparation of optionally substituted benzaldehyde dialkyl acetals | BAYER AKTIENGESELLSCHAFT (DE) | 1982-03-09 | — | — | US | disclosed |
| EP-0012240-B1 | PROCESS FOR MANUFACTURING OF OPTIONALLY SUBSTITUTED BENZALDEHYD-DIALKYL ACETALS | BAYER AG (DE) | 1982-01-20 | — | — | EP | disclosed |
| EP-0012240-A2 | Process for manufacturing of optionally substituted benzaldehyd-dialkyl acetals | BAYER AG (DE) | 1980-06-25 | — | — | EP | disclosed |
| US-4181659-A | Bis-penicillanoyloxy-alkanes | LEO PHARMACEUTICAL PRODUCTS LTD. A/S (DK) | 1980-01-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170210761-A1 | 9H-PYRIMIDO [4,5-B]INDOLES AND RELATED ANALOGS AS BET BROMODOMAIN INHIBITORS | BRD4, BRD3, BRD1 | BACE1 1160/4885PIN1 3249/4885PTPN1 3252/4885 |
| US-20110269985-A1 | ISOTOPICALLY LABELED COMPOSITIONS AND METHOD | SRMS, NES, RPS27A | BACE1 2613/4885PIN1 784/4885PTPN1 4513/4885 |
| US-20210347790-A1 | COMPOUND AND COLOR CONVERSION FILM COMPRISING SAME | BLVRB, CDYL, CRY1 | BACE1 168/4885PIN1 377/4885PTPN1 2846/4885 |
| US-11858952-B2 | Compound and color conversion film comprising same | BLVRB, CDYL, CRY1 | BACE1 168/4885PIN1 377/4885PTPN1 2846/4885 |
| US-20150246923-A1 | 9H-PYRIMIDO[4,5-B]INDOLES AND RELATED ANALOGS AS BET BROMODOMAIN INHIBITORS | BRD4, BRD3, BRD1 | BACE1 1160/4885PIN1 3249/4885PTPN1 3252/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.