Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.62 |
| ▸ | TDP2 | O95551 | 1/20 | 0.55 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.55 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.50 |
| ▸ | ABL1 | P00519 | 1/20 | 0.50 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.50 |
| ▸ | BCR | P11274 | 1/20 | 0.50 |
| ▸ | SRC | P12931 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9566631 | 0.92 | MEN1 (0.56) | MEN1KMT2ATDP2ADORA1KCNMA1 | |
| SCHEMBL9566416 | 0.84 | LMNA (0.59) | MEN1KMT2AADORA1NPC1KDM4E | |
| SCHEMBL11591966 | 0.82 | LMNA (0.69) | MEN1KMT2ANPC1LMNATDP1 | |
| SCHEMBL14880012 | 0.79 | MEN1 (0.89) | MEN1KMT2ANPC1L3MBTL1LMNA | |
| SCHEMBL9566457 | 0.78 | SMN1; SMN2 (0.55) | MEN1KMT2AKCNMA1NPC1LMNA | |
| SCHEMBL9566608 | 0.78 | NPC1 (0.58) | MEN1KMT2AKCNMA1NPC1L3MBTL1 | |
| SCHEMBL21934996 | 0.77 | KCNMA1 (0.61) | MEN1KMT2AKCNMA1NPC1L3MBTL1 | |
| SCHEMBL17040259 | 0.77 | LMNA (0.57) | MEN1KMT2ANPC1KDM4ELMNA | |
| SCHEMBL10822553 | 0.77 | KMT2A (0.56) | MEN1KMT2AKCNMA1NPC1L3MBTL1 | |
| SCHEMBL1937371 | 0.76 | GRM5 (0.62) | MEN1KMT2AKCNMA1NPC1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4333933-A | ANTIINFLAMMATORY, REACTING HALO BENZOGUANAMINE WITH NICOTINE ACID DERIVAGIVE | NIPPON SHINYAKU CO., LTD. (JP) | 1982-06-08 | — | — | US | disclosed |