Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTRB1 | P17538 | 1/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | ACE | P12821 | 3/20 | 0.58 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.54 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | YAP1 | P46937 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | PPARG | P37231 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30439776 | 0.93 | CTRB1 (0.74) | CTRB1KDM4ELMNAACENPSR1 | |
| SCHEMBL5710778 | 0.93 | CTRB1 (0.74) | CTRB1KDM4ELMNAACENPSR1 | |
| SCHEMBL7702739 | 0.91 | CTRB1 (0.69) | CTRB1KDM4ELMNAACENPSR1 | |
| SCHEMBL6367959 | 0.88 | CTRB1 (0.62) | CTRB1NPSR1ALDH1A1MAPT | |
| SCHEMBL21429800 | 0.86 | YAP1 (0.59) | CTRB1KDM4ELMNAACENPSR1 | |
| SCHEMBL19639223 | 0.84 | CTRB1 (0.67) | CTRB1KDM4ELMNAACENPSR1 | |
| SCHEMBL11434855 | 0.83 | CTRB1 (0.60) | CTRB1KDM4ELMNANPSR1ALDH1A1 | |
| SCHEMBL11434851 | 0.83 | CTRB1 (0.60) | CTRB1KDM4ELMNANPSR1ALDH1A1 | |
| SCHEMBL24513611 | 0.82 | CTRB1 (0.64) | CTRB1KDM4ELMNANPSR1ALDH1A1 | |
| SCHEMBL11167627 | 0.82 | CTRB1 (0.64) | CTRB1KDM4ELMNANPSR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4350628-A | OXIDATIVE DEHYDROGENATION WITH A BENZOQUINONE | RESEARCH CORPORATION (US) | 1982-09-21 | — | — | US | disclosed |
| US-4283328-A | TREATING AN N-BLOCKED AMINO ACID RESIDUE WITH A TETRAMETHYL GUANIDINIUM SALT OF A PEPTIDE CHAIN | RESEARCH CORPORATION (US) | 1981-08-11 | — | — | US | disclosed |
| US-4261884-A | DESIRABLE BIOLOGICAL PROPERTIES AND STABILITY TO ENZYME CLEAVAGE | RESEARCH CORPORATION (US) | 1981-04-14 | — | — | US | disclosed |