Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | QPCT | Q16769 | 1/20 | 0.48 |
| ▸ | TBXAS1 | P24557 | 6/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | NOS1 | P29475 | 1/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.46 |
| ▸ | LTA4H | P09960 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11243811 | 0.86 | MEN1 (0.51) | ALDH1A1KDM4EMAPK1QPCTGAA | |
| SCHEMBL11241723 | 0.83 | ALDH1A1 (0.54) | ALDH1A1KDM4ELMNAMAPK1QPCT | |
| SCHEMBL11243548 | 0.83 | ALDH1A1 (0.53) | ALDH1A1KDM4ELMNAMAPK1QPCT | |
| SCHEMBL11246686 | 0.82 | TP53 (0.47) | ALDH1A1KDM4EQPCTCYP19A1 | |
| SCHEMBL11241448 | 0.82 | QPCT (0.46) | ALDH1A1KDM4EQPCTMEN1KMT2A | |
| SCHEMBL11243518 | 0.81 | TBXAS1 (0.47) | ALDH1A1MAPK1QPCTTBXAS1MEN1 | |
| SCHEMBL11251785 | 0.81 | KDM4E (0.49) | ALDH1A1KDM4ELMNAQPCTGAA | |
| SCHEMBL11249800 | 0.80 | MEN1 (0.55) | ALDH1A1KDM4ELMNAQPCTGAA | |
| SCHEMBL11244013 | 0.79 | LMNA (0.42) | ALDH1A1KDM4ELMNAQPCTCYP19A1 | |
| SCHEMBL11243657 | 0.79 | MEN1 (0.54) | ALDH1A1KDM4ELMNAQPCTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0049565-A2 | Derivatives of substituted N-alkylimidazoles, their preparation and pharmaceutical compositions containing them | SYNTEX (U.S.A.) INC. (US) | 1982-04-14 | — | — | EP | disclosed |
| US-4321272-A | Derivatives of substituted N-alkylimidazoles | SYNTEX (U.S.A.) INC. (US) | 1982-03-23 | — | — | US | disclosed |