Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 3/20 | 0.39 |
| ▸ | CES2 | O00748 | 2/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.38 |
| ▸ | FFAR3 | O14843 | 3/20 | 0.38 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.36 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | CTSD | P07339 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11243321 | 1.00 | CES1 (0.39) | CES1CES2HDAC3HDAC1HDAC2 | |
| SCHEMBL5423161 | 0.83 | GRIK1 (0.41) | CES1CES2HDAC3HDAC1HDAC2 | |
| SCHEMBL1003142 | 0.80 | GRIK1 (0.50) | CES1CES2HDAC3HDAC1HDAC2 | |
| SCHEMBL9493661 | 0.80 | GRIK1 (0.50) | CES1CES2HDAC3HDAC1HDAC2 | |
| SCHEMBL691600 | 0.80 | GRIK1 (0.50) | CES1CES2HDAC3HDAC1HDAC2 | |
| SCHEMBL25932051 | 0.80 | CES1 (0.52) | CES1CES2HDAC3HDAC1HDAC2 | |
| SCHEMBL10062287 | 0.79 | — | — | |
| SCHEMBL11288814 | 0.78 | GRIK1 (0.39) | CES1CES2HDAC3HDAC1HDAC2 | |
| SCHEMBL11288817 | 0.78 | GRIK1 (0.39) | CES1CES2HDAC3HDAC1HDAC2 | |
| SCHEMBL9624867 | 0.78 | TSHR (0.46) | CES1CES2HDAC3HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109111411-A | A kind of light takes out layer material and its application | 武汉尚赛光电科技有限公司 | 2019-01-01 | — | — | CN | disclosed |
| CN-1498218-A | Imidazo-pyrimidine derivatives as GABA receptor ligands | Ĭ�ˡ�����-��ķ��˾ | 2004-05-19 | — | — | CN | disclosed |
| CN-1286251-A | Method for preparing 5-lipooxygenase inhibitor having changeable heterocycle system | PFIZER PROD INC (US) | 2001-03-07 | — | — | CN | disclosed |
| US-4315032-A | ANTITHROMBOGENIC AGENTS, ANTIULCER AGENTS | TEITIN LIMITED (JP) | 1982-02-09 | — | — | US | disclosed |
| EP-0019475-A2 | Process for preparing adjacently disubstituted ketones, novel prostaglandins E1 and anti-thrombotic compositions containing them | TEIJIN LIMITED (JP) | 1980-11-26 | — | — | EP | disclosed |
| US-4139717-A | 1,3-Dicarbonyl compounds | TEIJIN LIMITED (JP) | 1979-02-13 | — | — | US | disclosed |
| US-4009196-A | HYPOTENSIVE AGENTS, BRONCHODILATORS, PROSTAGLANDIN ANALOGS | TEIJIN LIMITED (JA) | 1977-02-22 | — | — | US | disclosed |