Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | HTR1A | P08908 | 1/20 | 0.30 |
| ▸ | DPP4 | P27487 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11250471 | 0.93 | L3MBTL1 (0.42) | TSHRMAPK1SMN1; SMN2L3MBTL1HTR1A | |
| SCHEMBL1594432 | 0.88 | L3MBTL1 (0.43) | TSHRMAPK1SMN1; SMN2L3MBTL1HTR1A | |
| SCHEMBL11252318 | 0.88 | MAPK1 (0.40) | TSHRMAPK1SMN1; SMN2L3MBTL1SLC6A4 | |
| SCHEMBL11246022 | 0.85 | SLC6A4 (0.34) | MAPK1SLC6A4 | |
| SCHEMBL11244126 | 0.84 | L3MBTL1 (0.31) | L3MBTL1 | |
| SCHEMBL14779412 | 0.83 | MMP2 (0.42) | TSHRMAPK1SMN1; SMN2L3MBTL1 | |
| SCHEMBL27590402 | 0.83 | OPRM1 (0.38) | TSHRMAPK1SMN1; SMN2L3MBTL1 | |
| SCHEMBL10339449 | 0.82 | L3MBTL1 (0.46) | TSHRMAPK1SMN1; SMN2L3MBTL1 | |
| SCHEMBL14778886 | 0.82 | MMP2 (0.44) | — | |
| SCHEMBL14780186 | 0.82 | MMP2 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0049565-A2 | Derivatives of substituted N-alkylimidazoles, their preparation and pharmaceutical compositions containing them | SYNTEX (U.S.A.) INC. (US) | 1982-04-14 | — | — | EP | disclosed |
| US-4321272-A | Derivatives of substituted N-alkylimidazoles | SYNTEX (U.S.A.) INC. (US) | 1982-03-23 | — | — | US | disclosed |