Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | FYN | P06241 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | MMP8 | P22894 | 1/20 | 0.38 |
| ▸ | CA6 | P23280 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL88340 | 0.64 | LMNA (0.64) | ALDH1A1LMNATP53HPGDALOX15 | |
| Pyrogallol SCHEMBL17964345 | 0.63 | ALDH1A1 (0.92) | ALDH1A1LMNATP53HPGDALOX15 | |
| SCHEMBL1244366 | 0.62 | LMNA (0.61) | ALDH1A1LMNATP53HPGDALOX15 | |
| SCHEMBL37622 | 0.61 | ALOX15 (0.58) | ALDH1A1LMNATP53HPGDALOX15 | |
| SCHEMBL7477685 | 0.61 | LMNA (0.58) | ALDH1A1LMNATP53HPGDALOX15 | |
| SCHEMBL5595646 | 0.61 | ALDH1A1 (0.58) | ALDH1A1LMNATP53HPGDALOX15 | |
| SCHEMBL10611186 | 0.61 | ALDH1A1 (0.58) | ALDH1A1LMNATP53HPGDALOX15 | |
| SCHEMBL1788357 | 0.61 | LMNA (0.58) | ALDH1A1LMNATP53HPGDALOX15 | |
| 3-Methoxycatechol SCHEMBL67332 | 0.61 | TP53 (1.00) | ALDH1A1LMNATP53HPGDALOX15 | |
| 3-Methoxycatechol SCHEMBL29477155 | 0.61 | TP53 (1.00) | ALDH1A1LMNATP53HPGDALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4356207-A | Sweetening with 5-(dihydroxyphenoxy) tetrazoles | ELI LILLY AND COMPANY (US) | 1982-10-26 | — | — | US | disclosed |
| US-4309446-A | 5-(Dihydroxyphenoxy)tetrazoles and use as sweeteners for medical compositions | ELI LILLY AND COMPANY (US) | 1982-01-05 | — | — | US | disclosed |