Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2C | Q5R387 | 6/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | LPAR1 | Q92633 | 3/20 | 0.42 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | LPAR5 | Q9H1C0 | 2/20 | 0.40 |
| ▸ | LPAR6 | P43657 | 1/20 | 0.40 |
| ▸ | LPAR4 | Q99677 | 1/20 | 0.40 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.40 |
| ▸ | TLR2 | O60603 | 1/20 | 0.40 |
| ▸ | AKT1 | P31749 | 1/20 | 0.40 |
| ▸ | AKT2 | P31751 | 1/20 | 0.40 |
| ▸ | AKT3 | Q9Y243 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10940945 | 0.86 | USP2 (0.51) | PLA2G2CUSP2LPAR1LPAR3AKT1 | |
| SCHEMBL1470040 | 0.81 | ALDH1A1 (0.40) | PLA2G2CUSP2LPAR1LPAR3 | |
| SCHEMBL10831321 | 0.79 | EPHX1 (0.51) | PLA2G2CUSP2LPAR1LPAR3HTT | |
| SCHEMBL1469678 | 0.78 | PLA2G2C (0.48) | PLA2G2CUSP2LPAR1LPAR3HTT | |
| SCHEMBL10941828 | 0.77 | USP2 (0.51) | PLA2G2CUSP2LPAR1LPAR3 | |
| SCHEMBL10943913 | 0.77 | USP2 (0.56) | PLA2G2CUSP2LPAR1LPAR3HTT | |
| SCHEMBL11244338 | 0.76 | PLA2G2C (0.42) | PLA2G2CUSP2HTTCES2 | |
| SCHEMBL11294443 | 0.76 | PLA2G2C (0.55) | PLA2G2CUSP2LPAR1LPAR3HTT | |
| SCHEMBL22272180 | 0.76 | USP2 (0.38) | PLA2G2CUSP2LPAR1LPAR3HTT | |
| SCHEMBL1469545 | 0.75 | NAAA (0.44) | PLA2G2CCES2AKT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4332729-A | CATALYZED CYCLIZATION | THE DOW CHEMICAL COMPANY (US) | 1982-06-01 | — | — | US | disclosed |
| US-4331604-A | Preparation of cyclic carbonates | THE DOW CHEMICAL COMPANY (US) | 1982-05-25 | — | — | US | disclosed |