Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2C | Q5R387 | 6/20 | 0.42 |
| ▸ | CES2 | O00748 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | NAAA | Q02083 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28655911 | 0.78 | ALDH1A1 (0.48) | MAPTTSHRALDH1A1 | |
| SCHEMBL31112705 | 0.78 | ZDHHC7 (0.42) | MAPTNAAAEPHX1 | |
| SCHEMBL31112232 | 0.78 | ZDHHC7 (0.42) | MAPTNAAAEPHX1 | |
| SCHEMBL11244332 | 0.76 | PLA2G2C (0.46) | PLA2G2CCES2HTTUSP2 | |
| SCHEMBL31112280 | 0.76 | ZDHHC7 (0.40) | MAPTNAAAALDH1A1 | |
| SCHEMBL31112680 | 0.76 | NAAA (0.48) | NAAAEPHX1TSHRALDH1A1 | |
| SCHEMBL31112696 | 0.76 | NAAA (0.48) | NAAAEPHX1TSHRALDH1A1 | |
| SCHEMBL30288172 | 0.75 | MEN1 (0.46) | PLA2G2CCES2MEN1THRBHTT | |
| SCHEMBL10940945 | 0.74 | USP2 (0.51) | PLA2G2CMAPTUSP2 | |
| SCHEMBL28609396 | 0.73 | FAAH (0.42) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4332729-A | CATALYZED CYCLIZATION | THE DOW CHEMICAL COMPANY (US) | 1982-06-01 | — | — | US | disclosed |
| US-4331604-A | Preparation of cyclic carbonates | THE DOW CHEMICAL COMPANY (US) | 1982-05-25 | — | — | US | disclosed |