Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | BLM | P54132 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.39 |
| ▸ | GABRP | O00591 | 1/20 | 0.39 |
| ▸ | GABRD | O14764 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.39 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.39 |
| ▸ | GABRR2 | P28476 | 1/20 | 0.39 |
| ▸ | SLC6A1 | P30531 | 1/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3720306 | 0.91 | LMNA (0.45) | TSHRLMNABLMCYP1A2THRB | |
| Ammonia Solution, Strong SCHEMBL549097 | 0.88 | LMNA (0.43) | TSHRLMNABLMCYP1A2THRB | |
| Ether SCHEMBL16594516 | 0.84 | CYP1A2 (0.41) | TSHRLMNABLMCYP1A2THRB | |
| SCHEMBL17255235 | 0.81 | NFKB1 (0.48) | TSHRLMNABLMCYP1A2THRB | |
| SCHEMBL24807012 | 0.79 | CYP1A2 (0.41) | TSHRLMNABLMCYP1A2THRB | |
| SCHEMBL5584073 | 0.79 | — | — | |
| SCHEMBL466897 | 0.74 | — | — | |
| Ethylene Glycol SCHEMBL19467762 | 0.73 | — | — | |
| SCHEMBL20009593 | 0.72 | LMNA (0.33) | TSHRLMNABLMCYP1A2THRB | |
| SCHEMBL13461953 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4313004-A | CATALYTIC HYDROGENATION, BY-PRODUCT INHIBITION | MILLIKEN RESEARCH CORPORATION (US) | 1982-01-26 | — | — | US | claimed |
| US-4313004-A | CATALYTIC HYDROGENATION, BY-PRODUCT INHIBITION | MILLIKEN RESEARCH CORPORATION (US) | 1982-01-26 | — | — | US | disclosed |