SCHEMBL3720306

SCHEMBL3720306

C=C(CCCN)CCCN

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.45
BLM P54132 4/20 0.45
TSHR P16473 2/20 0.45
THRB P10828 2/20 0.45
KMT2A Q03164 2/20 0.45
NPSR1 Q6W5P4 2/20 0.45
CYP1A2 P05177 2/20 0.45
GABBR2 O75899 2/20 0.45
GABRR1 P24046 2/20 0.45
GABBR1 Q9UBS5 2/20 0.45
GABRR3 A8MPY1 1/20 0.45
GABRP O00591 1/20 0.45
GABRD O14764 1/20 0.45
HDAC3 O15379 1/20 0.45
GABRA1 P14867 1/20 0.45
GABRB1 P18505 1/20 0.45
GABRG2 P18507 1/20 0.45
GABRB3 P28472 1/20 0.45
GABRR2 P28476 1/20 0.45
SLC6A1 P30531 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL549097 0.97 LMNA (0.43) LMNABLMTSHRTHRBKMT2A
Ethylene Glycol SCHEMBL11244397 0.91 TSHR (0.39) LMNABLMTSHRTHRBKMT2A
SCHEMBL17255235 0.90 NFKB1 (0.48) LMNABLMTSHRTHRBKMT2A
SCHEMBL5584073 0.87
SCHEMBL24807012 0.87 CYP1A2 (0.41) LMNABLMTSHRTHRBKMT2A
SCHEMBL466897 0.82
SCHEMBL20009593 0.80 LMNA (0.33) LMNABLMTSHRTHRBKMT2A
SCHEMBL21698637 0.78 DNM1 (0.50) LMNABLMTSHRTHRBKMT2A
SCHEMBL4108533 0.77
SCHEMBL6418109 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2332590-B1 Non-degradable low swelling, water soluble radiopaque hydrogels TRIVASCULAR INC (US) 2014-08-27 EP claimed
CN-109867852-A The manufacturing method of lining material, cable and cable 日立金属株式会社 2019-06-11 CN disclosed
CN-104744793-B Encapsulating material for solar cell resin combination, encapsulating material for solar cell and solar cell module 东洋油墨SC控股株式会社 2018-10-02 CN disclosed
CN-101650451-B Light conducting plate SUMITOMO CHEMICAL CO 2015-04-29 CN disclosed
CN-102066452-B Polyamine having reduced blushing effect, and use thereof as curing agent for epoxy resins SIKA TECHNOLOGY AG 2014-05-14 CN disclosed
EP-1771548-B1 USE OF DENDRIMERS TO STIMULATE CELL GROWTH CENTRE NAT RECH SCIENT (FR) 2012-06-27 EP disclosed
WO-2010076490-A2 COSMETIC COMPOSITION CONTAINING A POLYAMINE HAVING DIAZIRINE GROUPS, AND USE THEREOF FOR PHOTO-GRAFTING A NON-SACCHARIDE POLYMER OTHER THAN POLYAMINE POLYMERS L' OREAL (FR) 2010-07-08 WO disclosed
WO-2010076489-A2 COSMETIC COMPOSITION CONTAINING A POLYAMINE HAVING DIAZIRINE GROUPS AND USE THEREOF FOR PHOTO-GRAFTING PIGMENTS AND/OR MICRO- OR NANOPARTICLES L'OREAL (FR) 2010-07-08 WO disclosed
WO-2009118492-A1 RANDOM ETHYLENE POLYMER INCLUDING A REACTION GROUP AND A SILICONIZED GROUP, COSMETIC COMPOSITION AND COSMETIC TREATMENT METHOD L'OREAL (FR) 2009-10-01 WO disclosed
WO-2009106781-A2 COSMETIC COMPOSITION CONTAINING A RANDOM ETHYLENIC POLYMER CONTAINING A REACTIVE GROUP AND AN IONISABLE GROUP, COSMETIC TREATMENT METHOD AND NOVEL POLYMERS L'OREAL (FR) 2009-09-03 WO disclosed
WO-2009106782-A2 COSMETIC COMPOSITION CONTAINING A RANDOM ETHYLENIC POLYMER WITH A REACTIVE GROUP, AND COSMETIC TREATMENT METHOD L'OREAL (FR) 2009-09-03 WO disclosed
EP-0884047-B1 Use of some polyamine polymers as antioxidant agents OREAL (FR) 2005-06-15 EP disclosed
EP-0880963-B1 Association of a retionoid with a polyamino-polymer OREAL (FR) 2002-01-30 EP disclosed
EP-0880961-B1 Composition comprising a derivative of cinnamic acid and a polyamino-polymer OREAL (FR) 2001-03-07 EP disclosed
EP-0880962-B1 Compositions comprising a derivative of dibenzoylmethane and a polymino-polymer OREAL (FR) 2001-01-31 EP disclosed
EP-0884047-A1 Use of some polyamine polymers as antioxidant agents L'OREAL (FR) 1998-12-16 EP disclosed
EP-0880962-A2 Compositions comprising a derivative of dibenzoylmethane and a polymino-polymer L'OREAL (FR) 1998-12-02 EP disclosed
EP-0880961-A2 Composition comprising a derivative of cinnamic acid and a polyamino-polymer L'OREAL (FR) 1998-12-02 EP disclosed
EP-0880963-A2 Association of a retionoid with a polyamino-polymer L'OREAL (FR) 1998-12-02 EP disclosed
US-4247426-A Polyamides EMERY INDUSTRIES, INC. (US) 1981-01-27 US disclosed