Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL549097

C=C(CCCN)CCCN.N.N

nearest known ligand 0.43

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.43
BLM P54132 3/20 0.43
TSHR P16473 2/20 0.43
CYP1A2 P05177 2/20 0.43
THRB P10828 2/20 0.43
KMT2A Q03164 2/20 0.43
NPSR1 Q6W5P4 2/20 0.43
GABRR3 A8MPY1 1/20 0.43
GABRP O00591 1/20 0.43
GABRD O14764 1/20 0.43
HDAC3 O15379 1/20 0.43
GABBR2 O75899 1/20 0.43
GABRA1 P14867 1/20 0.43
GABRB1 P18505 1/20 0.43
GABRG2 P18507 1/20 0.43
GABRR1 P24046 1/20 0.43
GABRB3 P28472 1/20 0.43
GABRR2 P28476 1/20 0.43
SLC6A1 P30531 1/20 0.43
GABRA5 P31644 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3720306 0.97 LMNA (0.45) LMNABLMTSHRCYP1A2THRB
Ethylene Glycol SCHEMBL11244397 0.88 TSHR (0.39) LMNABLMTSHRCYP1A2THRB
SCHEMBL17255235 0.87 NFKB1 (0.48) LMNABLMTSHRCYP1A2THRB
SCHEMBL27394845 0.85 TSHR (0.38) LMNABLMTSHRCYP1A2THRB
SCHEMBL24807012 0.84 CYP1A2 (0.41) LMNABLMTSHRCYP1A2THRB
SCHEMBL5584073 0.84
SCHEMBL26522108 0.83
SCHEMBL466897 0.79
SCHEMBL20009593 0.77 LMNA (0.33) LMNABLMTSHRCYP1A2THRB
SCHEMBL21698637 0.75 DNM1 (0.50) LMNABLMTSHRTHRBKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 99 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5223370-A Low gloss toner compositions and processes thereof XEROX CORPORATION (US) 1993-06-29 US claimed
US-5114819-A Magnetic encapsulated toner compositions XEROX CORPORATION (US) 1992-05-19 US claimed
US-5043240-A Encapsulated toner compositions XEROX CORPORATION (US) 1991-08-27 US claimed
US-5037716-A Encapsulated toners and processes thereof XEROX CORPORATION (US) 1991-08-06 US claimed
EP-0343852-A2 Cold pressure fixable toner compositions XEROX CORPORATION (US) 1989-11-29 EP claimed
US-4877706-A CORE CONTAINING POLYMER AND MAGNETIC PIGMENT PARTICLES ENCAPSULATED WITH A POLYUREA XEROX CORPORATION (US) 1989-10-31 US claimed
EP-4247824-A1 ACYLPHOSPHINE OXIDE PHOTOINITIATORS AND APPLICATIONS THEREOF AGFA NV (BE) 2023-09-27 EP disclosed
EP-4247903-A1 UV CURABLE INKJET INKS AND INKJET PRINTING METHODS AGFA NV (BE) 2023-09-27 EP disclosed
WO-2022106100-A1 UV CURABLE INKJET INKS AND INKJET PRINTING METHODS AGFA NV (BE) 2022-05-27 WO disclosed
WO-2022106099-A1 ACYLPHOSPHINE OXIDE PHOTOINITIATORS AND APPLICATIONS THEREOF AGFA NV (BE) 2022-05-27 WO disclosed
EP-3986600-A1 HOLLOW FIBER MEMBRANE Lubrizol Advanced Materials, Inc. (US) 2022-04-27 EP disclosed
EP-3883885-A1 GRAPHENE PRODUCTION AND COMPOSITION The Lubrizol Corporation (US) 2021-09-29 EP disclosed
EP-3813991-A1 FLAT SHEET POROUS PVC MEMBRANE Lubrizol Advanced Materials, Inc. (US) 2021-05-05 EP disclosed
US-5043240-A Encapsulated toner compositions XEROX CORPORATION (US) 1991-08-27 US disclosed
EP-0416897-A2 Encapsulated toner compositions XEROX CORPORATION (US) 1991-03-13 EP disclosed
US-4925974-A REACTING PARTIALLY BLOCKED POLYISOCYANATE WITH POLYAMINE; ISOLATING HUELS AKTIENGESELLSCHAFT (DE) 1990-05-15 US disclosed
EP-0343852-A2 Cold pressure fixable toner compositions XEROX CORPORATION (US) 1989-11-29 EP disclosed
EP-0343852-A2 Cold pressure fixable toner compositions XEROX CORPORATION (US) 1989-11-29 EP disclosed
US-4877706-A CORE CONTAINING POLYMER AND MAGNETIC PIGMENT PARTICLES ENCAPSULATED WITH A POLYUREA XEROX CORPORATION (US) 1989-10-31 US disclosed
US-4877706-A CORE CONTAINING POLYMER AND MAGNETIC PIGMENT PARTICLES ENCAPSULATED WITH A POLYUREA XEROX CORPORATION (US) 1989-10-31 US disclosed