Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.34 |
| ▸ | CHRNG | P07510 | 1/20 | 0.34 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.34 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
| ▸ | CHRND | Q07001 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.31 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10676662 | 0.84 | MAOB (0.42) | MAOBMAOAGSK3BCHRNA1CHRNG | |
| SCHEMBL9518055 | 0.84 | MAOB (0.42) | MAOBMAOAGSK3BCHRNA1CHRNG | |
| SCHEMBL11238036 | 0.84 | MAOB (0.34) | MAOBMAOAGSK3BCHRNA1CHRNG | |
| SCHEMBL11234671 | 0.83 | L3MBTL1 (0.38) | CA12CA1CA2CA7CA9 | |
| SCHEMBL11230749 | 0.83 | MAOA (0.33) | MAOBMAOASIRT2GSK3BCHRNA1 | |
| SCHEMBL11237185 | 0.82 | MAOB (0.37) | MAOBMAOASIRT2GSK3BCHRNA1 | |
| SCHEMBL11236878 | 0.81 | SOAT1 (0.37) | MAOBMAOACHRNA1CHRNGCHRNB1 | |
| SCHEMBL11250705 | 0.80 | MAOB (0.39) | MAOBMAOASIRT2GSK3BCHRNA1 | |
| SCHEMBL11247712 | 0.78 | MAOB (0.37) | MAOBMAOASIRT2GSK3BCHRNA1 | |
| SCHEMBL11248824 | 0.77 | GRIN1 (0.43) | MAOBMAOASIRT2GSK3BCHRNA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0049565-A2 | Derivatives of substituted N-alkylimidazoles, their preparation and pharmaceutical compositions containing them | SYNTEX (U.S.A.) INC. (US) | 1982-04-14 | — | — | EP | disclosed |
| US-4321272-A | Derivatives of substituted N-alkylimidazoles | SYNTEX (U.S.A.) INC. (US) | 1982-03-23 | — | — | US | disclosed |