Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 1/20 | 0.40 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.40 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.40 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.40 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | CTSS | P25774 | 2/20 | 0.37 |
| ▸ | NPBWR1 | P48145 | 5/20 | 0.36 |
| ▸ | PDE2A | O00408 | 1/20 | 0.36 |
| ▸ | CBFB | Q13951 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11258703 | 0.90 | PIM1 (0.33) | PIM1CSNK2A2CSNK2BPIM3PIM2 | |
| SCHEMBL11245732 | 0.87 | GUSB (0.45) | PIM1CSNK2A2CSNK2BPIM3PIM2 | |
| SCHEMBL11245574 | 0.87 | NT5E (0.41) | PIM1CSNK2A2CSNK2BPIM3PIM2 | |
| SCHEMBL11241077 | 0.84 | MPL (0.44) | NPBWR1PDE2A | |
| SCHEMBL11250776 | 0.84 | ABCC8 (0.44) | NPBWR1CBFBPTGES | |
| SCHEMBL11250270 | 0.82 | TRPV4 (0.34) | PIM1CSNK2A2CSNK2BPIM3PIM2 | |
| SCHEMBL11250888 | 0.81 | PIM1 (0.42) | PIM1CSNK2A2CSNK2BPIM3PIM2 | |
| SCHEMBL11246193 | 0.79 | TEK (0.43) | KMT2A | |
| SCHEMBL11250921 | 0.79 | EPAS1 (0.39) | PIM1CSNK2A2CSNK2BPIM3PIM2 | |
| SCHEMBL11246007 | 0.79 | CHEK2 (0.35) | PIM1CSNK2A2CSNK2BPIM3PIM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4314844-A | FUNGICIDES | ROHM AND HAAS COMPANY (US) | 1982-02-09 | — | — | US | disclosed |