Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 3/20 | 0.33 |
| ▸ | CSNK2A2 | P19784 | 3/20 | 0.33 |
| ▸ | CSNK2B | P67870 | 3/20 | 0.33 |
| ▸ | PIM3 | Q86V86 | 3/20 | 0.33 |
| ▸ | PIM2 | Q9P1W9 | 3/20 | 0.33 |
| ▸ | CTSS | P25774 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.31 |
| ▸ | PDE2A | O00408 | 5/20 | 0.31 |
| ▸ | PTGES | O14684 | 3/20 | 0.31 |
| ▸ | CBFB | Q13951 | 1/20 | 0.31 |
| ▸ | GUSB | P08236 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11244602 | 0.90 | PIM1 (0.40) | PIM1CSNK2A2CSNK2BPIM3PIM2 | |
| SCHEMBL11257518 | 0.86 | NPBWR1 (0.31) | — | |
| SCHEMBL11260493 | 0.85 | MPL (0.36) | PDE2A | |
| SCHEMBL11245574 | 0.83 | NT5E (0.41) | PIM1CSNK2A2CSNK2BPIM3PIM2 | |
| SCHEMBL11245732 | 0.83 | GUSB (0.45) | PIM1CSNK2A2CSNK2BPIM3PIM2 | |
| SCHEMBL11250270 | 0.78 | TRPV4 (0.34) | PIM1CSNK2A2CSNK2BPIM3PIM2 | |
| SCHEMBL11246193 | 0.78 | TEK (0.43) | KMT2A | |
| SCHEMBL11250888 | 0.77 | PIM1 (0.42) | PIM1CSNK2A2CSNK2BPIM3PIM2 | |
| SCHEMBL11247915 | 0.77 | PTGES (0.34) | PTGES | |
| SCHEMBL11262196 | 0.77 | NPBWR1 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4314844-A | FUNGICIDES | ROHM AND HAAS COMPANY (US) | 1982-02-09 | — | — | US | disclosed |