Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK2 | O96017 | 3/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.34 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 2/20 | 0.33 |
| ▸ | RARA | P10276 | 1/20 | 0.32 |
| ▸ | RARB | P10826 | 1/20 | 0.32 |
| ▸ | RARG | P13631 | 1/20 | 0.32 |
| ▸ | PIM1 | P11309 | 2/20 | 0.32 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.32 |
| ▸ | CSNK2B | P67870 | 2/20 | 0.32 |
| ▸ | PIM3 | Q86V86 | 2/20 | 0.32 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.32 |
| ▸ | GUSB | P08236 | 1/20 | 0.32 |
| ▸ | RORC | P51449 | 1/20 | 0.31 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11247954 | 0.87 | HDAC3 (0.35) | HDAC6HDAC3HDAC7HDAC10ACHE | |
| SCHEMBL11259416 | 0.86 | HDAC6 (0.34) | HDAC6HDAC4HDAC3HDAC7HDAC10 | |
| SCHEMBL11245992 | 0.86 | HDAC3 (0.41) | CHEK2HDAC6HDAC3HDAC7HDAC10 | |
| SCHEMBL11242243 | 0.84 | ALDH1A1 (0.46) | — | |
| SCHEMBL11245574 | 0.80 | NT5E (0.41) | PIM1CSNK2A2CSNK2BPIM3PIM2 | |
| SCHEMBL11245732 | 0.80 | GUSB (0.45) | PIM1CSNK2A2CSNK2BPIM3PIM2 | |
| SCHEMBL11254942 | 0.79 | PTGES (0.33) | — | |
| SCHEMBL11257669 | 0.79 | CES1 (0.40) | CHEK2HDAC6 | |
| SCHEMBL11244602 | 0.79 | PIM1 (0.40) | PIM1CSNK2A2CSNK2BPIM3PIM2 | |
| SCHEMBL11258703 | 0.75 | PIM1 (0.33) | PIM1CSNK2A2CSNK2BPIM3PIM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4314844-A | FUNGICIDES | ROHM AND HAAS COMPANY (US) | 1982-02-09 | — | — | US | disclosed |