Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATP4A | P20648 | 7/20 | 0.47 |
| ▸ | ATP4B | P51164 | 7/20 | 0.47 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.44 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.44 |
| ▸ | ABL1 | P00519 | 3/20 | 0.39 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.39 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.39 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.39 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.38 |
| ▸ | ELOVL1 | Q9BW60 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3599186 | 0.84 | ATP4A (0.61) | ATP4AATP4BROCK2ROCK1ABL1 | |
| SCHEMBL11245308 | 0.83 | ABL1 (0.41) | ATP4AATP4BABL1CSNK2A2CSNK2B | |
| SCHEMBL11244710 | 0.81 | PRMT6 (0.45) | ATP4AATP4BROCK2ROCK1PRMT6 | |
| SCHEMBL11244712 | 0.81 | PRMT6 (0.45) | ATP4AATP4BROCK2ROCK1PRMT6 | |
| SCHEMBL11260913 | 0.80 | ATP4A (0.39) | ATP4AATP4BROCK2ABL1MAPT | |
| SCHEMBL11257651 | 0.79 | GSTO1 (0.39) | ATP4AATP4BROCK2ABL1CSNK2A2 | |
| SCHEMBL11242112 | 0.79 | MAPT (0.44) | ABL1MAPTMEN1KMT2A | |
| SCHEMBL11242103 | 0.79 | MAPT (0.44) | ABL1MAPTMEN1KMT2A | |
| SCHEMBL10673686 | 0.79 | ABL1 (0.39) | ATP4AATP4BABL1MAPTMEN1 | |
| SCHEMBL11252869 | 0.79 | ATP4A (0.37) | ATP4AATP4BROCK2ABL1CSNK2A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4315009-A | Antisecretory guanidine derivatives and pharmaceutical compositions containing them | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1982-02-09 | — | — | US | disclosed |
| EP-0003640-B1 | ANTISECRETORY GUANIDINE DERIVATIVES, PROCESSES FOR THEIR MANUFACTURE AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1982-01-27 | — | — | EP | disclosed |
| EP-0003640-A2 | Antisecretory guanidine derivatives, processes for their manufacture and pharmaceutical compositions containing them | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1979-08-22 | — | — | EP | disclosed |