Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.32 |
| ▸ | RELA | Q04206 | 1/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.31 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11246825 | 0.82 | SMN1; SMN2 (0.33) | CNR2SMN1; SMN2NPC1LMNARAB9A | |
| SCHEMBL26699006 | 0.71 | PDE4A (0.34) | IDO1KMT2A | |
| SCHEMBL13056089 | 0.68 | RAB9A (0.54) | SMN1; SMN2NPC1LMNARAB9ATP53 | |
| SCHEMBL24491102 | 0.68 | ADORA3 (0.40) | SMN1; SMN2NPC1LMNARAB9ATP53 | |
| SCHEMBL25083853 | 0.67 | TLR7 (0.41) | IDO1MEN1KMT2A | |
| SCHEMBL20322050 | 0.67 | IDO1 (0.36) | IDO1POLB | |
| SCHEMBL11190347 | 0.66 | HTT (0.59) | SMN1; SMN2NPC1LMNARAB9ATP53 | |
| SCHEMBL9892988 | 0.66 | SMN1; SMN2 (0.49) | CNR2SMN1; SMN2NPC1LMNARAB9A | |
| SCHEMBL1884589 | 0.63 | ALDH1A1 (0.34) | NPC1LMNARAB9AADORA3ADORA2A | |
| SCHEMBL18529289 | 0.63 | FFAR2 (0.50) | KIF11SMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4353920-A | Use of selected 3-trihalomethyl-5-ureido-1,2,4-oxadiazoles and -1,2,4-thiadiazoles as agricultural viricides | OLIN CORPORATION (US) | 1982-10-12 | — | — | US | disclosed |