Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | C5AR1 | P21730 | 7/20 | 0.52 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | CTSV | O60911 | 3/20 | 0.46 |
| ▸ | CTSL | P07711 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ACP1 | P24666 | 1/20 | 0.43 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.43 |
| ▸ | PTPN13 | Q12923 | 1/20 | 0.43 |
| ▸ | SSU72 | Q9NP77 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | PPIA | P62937 | 1/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11269770 | 0.89 | CYP19A1 (0.43) | C5AR1CYP19A1KDM4EALDH1A1HPGD | |
| SCHEMBL11253653 | 0.87 | C5AR1 (0.55) | C5AR1CYP19A1KDM4ECTSVCTSL | |
| SCHEMBL11258869 | 0.85 | ALDH1A1 (0.46) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL11264325 | 0.82 | C5AR1 (0.60) | C5AR1CYP19A1KDM4ECTSVCTSL | |
| Hydrochloric Acid SCHEMBL11258213 | 0.81 | C5AR1 (0.59) | C5AR1CYP19A1KDM4ECTSVCTSL | |
| SCHEMBL11283867 | 0.81 | C5AR1 (0.58) | C5AR1CYP19A1KDM4EALDH1A1CTSV | |
| SCHEMBL11722594 | 0.81 | C5AR1 (0.54) | C5AR1CYP19A1KDM4ECTSVCTSL | |
| SCHEMBL11265836 | 0.80 | C5AR1 (0.63) | C5AR1ALDH1A1KMT2APOLBMAPT | |
| SCHEMBL11596780 | 0.80 | C5AR1 (0.62) | C5AR1CYP19A1KDM4EALDH1A1CTSV | |
| SCHEMBL11279359 | 0.79 | C5AR1 (0.56) | C5AR1CYP19A1KDM4EALDH1A1CTSV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4326074-A | ANTIDIARRHEA AGENTS | WILLIAM H. RORER, INC. (US) | 1982-04-20 | — | — | US | disclosed |