Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11235754 | 0.77 | MEN1 (0.40) | SMN1; SMN2TP53ALDH1A1MEN1CYP1A2 | |
| SCHEMBL11249308 | 0.76 | POLB (0.41) | SMN1; SMN2TP53ALDH1A1MEN1CYP1A2 | |
| SCHEMBL11243162 | 0.76 | SMN1; SMN2 (0.36) | SMN1; SMN2TP53ALDH1A1HPGDMEN1 | |
| SCHEMBL11241064 | 0.75 | MEN1 (0.43) | TP53ALDH1A1MEN1CYP1A2CYP2D6 | |
| SCHEMBL11237640 | 0.75 | MEN1 (0.36) | SMN1; SMN2ALDH1A1MEN1KMT2AGAA | |
| SCHEMBL11236106 | 0.74 | LMNA (0.41) | SMN1; SMN2TP53ALDH1A1MEN1CYP1A2 | |
| SCHEMBL11233822 | 0.74 | ALDH1A1 (0.42) | SMN1; SMN2TP53ALDH1A1HPGDMEN1 | |
| SCHEMBL11475408 | 0.73 | TBXAS1 (0.39) | SMN1; SMN2TP53MEN1CYP1A2CYP2D6 | |
| SCHEMBL11480623 | 0.72 | MAPK1 (0.41) | SMN1; SMN2ALDH1A1HPGDMEN1CYP1A2 | |
| SCHEMBL11480630 | 0.72 | MAPK1 (0.41) | SMN1; SMN2ALDH1A1HPGDMEN1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4329460-A | ANTICANCER AGENTS, ANTIVIRAL AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1982-05-11 | — | — | US | disclosed |