Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.69 |
| ▸ | MEN1 | O00255 | 2/20 | 0.69 |
| ▸ | NPC1 | O15118 | 2/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.69 |
| ▸ | CCNE1 | P24864 | 9/20 | 0.63 |
| ▸ | CDK2 | P24941 | 9/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | USP2 | O75604 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | PTGES | O14684 | 1/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11543404 | 0.95 | MEN1 (0.61) | RAB9AMEN1NPC1KMT2ACCNE1 | |
| SCHEMBL11240095 | 0.90 | KDM4E (0.60) | RAB9AMEN1NPC1KMT2ACCNE1 | |
| SCHEMBL11247047 | 0.86 | KDM4E (0.64) | RAB9AMEN1NPC1KMT2ACCNE1 | |
| SCHEMBL11250798 | 0.86 | ALDH1A1 (0.62) | RAB9AMEN1NPC1KMT2ACCNE1 | |
| SCHEMBL11249486 | 0.86 | KMT2A (0.69) | RAB9AMEN1NPC1KMT2ACCNE1 | |
| SCHEMBL11256945 | 0.83 | RAB9A (0.71) | RAB9AMEN1NPC1KMT2ACCNE1 | |
| SCHEMBL11540126 | 0.83 | MAPT (0.53) | RAB9AMEN1NPC1KMT2ACCNE1 | |
| SCHEMBL29528408 | 0.83 | RAB9A (0.76) | RAB9AMEN1NPC1KMT2ACCNE1 | |
| SCHEMBL3407292 | 0.82 | RAB9A (1.00) | RAB9AMEN1NPC1KMT2ACCNE1 | |
| SCHEMBL11247644 | 0.82 | CA1 (0.53) | RAB9AMEN1NPC1KMT2ACCNE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4325962-A | ANTIINFLAMMATORY AGENTS, ANALGESICS, ANTIDYRETICS | BYK-GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1982-04-20 | — | — | US | disclosed |
| US-4146721-A | ANALGESICS, ANTIINFLAMMATORY AGENTS AND ANTIPYRETICS | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1979-03-27 | — | — | US | disclosed |