Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | NPC1 | O15118 | 2/20 | 0.61 |
| ▸ | RAB9A | P51151 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | CCNE1 | P24864 | 7/20 | 0.56 |
| ▸ | CDK2 | P24941 | 7/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | AURKA | O14965 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11245692 | 0.95 | RAB9A (0.69) | MEN1NPC1RAB9AKMT2ACCNE1 | |
| SCHEMBL11240095 | 0.90 | KDM4E (0.60) | MEN1NPC1RAB9AKMT2ACCNE1 | |
| SCHEMBL11255300 | 0.86 | ALDH1A1 (0.55) | MEN1NPC1RAB9AKMT2ACCNE1 | |
| SCHEMBL11245465 | 0.86 | KDM4E (0.57) | KMT2ACCNE1CDK2KDM4EALDH1A1 | |
| SCHEMBL16040449 | 0.85 | CCNE1 (0.46) | MEN1NPC1RAB9AKMT2ACCNE1 | |
| SCHEMBL29528342 | 0.83 | RAB9A (0.68) | MEN1NPC1RAB9AKMT2ACCNE1 | |
| SCHEMBL11247889 | 0.82 | RAB9A (0.89) | MEN1NPC1RAB9AKMT2ACCNE1 | |
| SCHEMBL11247047 | 0.81 | KDM4E (0.64) | MEN1NPC1RAB9AKMT2ACCNE1 | |
| SCHEMBL11249486 | 0.81 | KMT2A (0.69) | MEN1NPC1RAB9AKMT2ACCNE1 | |
| SCHEMBL11250798 | 0.81 | ALDH1A1 (0.62) | MEN1NPC1RAB9AKMT2ACCNE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4146721-A | ANALGESICS, ANTIINFLAMMATORY AGENTS AND ANTIPYRETICS | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1979-03-27 | — | — | US | disclosed |