Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.53 |
| ▸ | NR2F2 | P24468 | 2/20 | 0.52 |
| ▸ | GALR3 | O60755 | 1/20 | 0.52 |
| ▸ | APP | P05067 | 1/20 | 0.51 |
| ▸ | EGFR | P00533 | 5/20 | 0.48 |
| ▸ | KRAS | P01116 | 3/20 | 0.48 |
| ▸ | SOS1 | Q07889 | 2/20 | 0.48 |
| ▸ | LDHA | P00338 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 4/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.47 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.47 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.47 |
| ▸ | LTK | P29376 | 1/20 | 0.47 |
| ▸ | GRK5 | P34947 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11245960 | 0.87 | NR2F2 (0.52) | ABCG2NR2F2GALR3EGFRLDHA | |
| SCHEMBL11254153 | 0.85 | LDHA (0.61) | ABCG2NR2F2GALR3EGFRLDHA | |
| SCHEMBL8497690 | 0.84 | NR2F2 (0.51) | ABCG2NR2F2GALR3APPEGFR | |
| SCHEMBL11256846 | 0.83 | NR2F2 (0.59) | ABCG2NR2F2GALR3APPEGFR | |
| SCHEMBL11250025 | 0.80 | NPC1 (0.52) | NR2F2GALR3EGFRKRASLDHA | |
| SCHEMBL9608143 | 0.79 | NR2F2 (0.46) | ABCG2NR2F2GALR3APPEGFR | |
| SCHEMBL11248882 | 0.79 | EGFR (0.52) | NR2F2GALR3EGFRKRASLDHA | |
| SCHEMBL11255628 | 0.79 | GBA1 (0.56) | ABCG2NR2F2GALR3APPEGFR | |
| SCHEMBL13283199 | 0.78 | GALR3 (0.63) | ABCG2NR2F2GALR3APPEGFR | |
| SCHEMBL4572178 | 0.78 | GALR3 (0.63) | ABCG2NR2F2GALR3APPEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4323680-A | 4-Aminoquinazoline compounds useful as agricultural fungicides | SANKYO COMPANY LIMITED (JP) | 1982-04-06 | — | — | US | disclosed |
| US-4213987-A | 4-AMINOQUINAZOLINES | SANKYO COMPANY LIMITED (JP) | 1980-07-22 | — | — | US | disclosed |