Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 1/20 | 0.56 |
| ▸ | NR2F2 | P24468 | 4/20 | 0.54 |
| ▸ | GALR3 | O60755 | 3/20 | 0.54 |
| ▸ | EGFR | P00533 | 5/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.48 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.48 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.48 |
| ▸ | ROS1 | P08922 | 1/20 | 0.48 |
| ▸ | FLT3 | P36888 | 1/20 | 0.48 |
| ▸ | ERBB4 | Q15303 | 1/20 | 0.48 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.48 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.47 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11256846 | 0.92 | NR2F2 (0.59) | GBA1NR2F2GALR3EGFRRAB9A | |
| SCHEMBL11250025 | 0.89 | NPC1 (0.52) | GBA1NR2F2GALR3EGFRRAB9A | |
| SCHEMBL11248882 | 0.88 | EGFR (0.52) | GBA1NR2F2GALR3EGFRRAB9A | |
| SCHEMBL11246634 | 0.86 | SMN1; SMN2 (0.51) | GBA1NR2F2GALR3EGFRRAB9A | |
| SCHEMBL11254153 | 0.81 | LDHA (0.61) | NR2F2GALR3EGFRRAB9ASMN1; SMN2 | |
| SCHEMBL11240075 | 0.81 | EGFR (0.53) | GBA1NR2F2GALR3EGFRRAB9A | |
| SCHEMBL11261278 | 0.80 | EGFR (0.52) | GBA1NR2F2GALR3EGFRRAB9A | |
| SCHEMBL11243265 | 0.79 | HTT (0.55) | GBA1NR2F2GALR3EGFRSMN1; SMN2 | |
| SCHEMBL11245960 | 0.79 | NR2F2 (0.52) | GBA1NR2F2GALR3EGFRRAB9A | |
| SCHEMBL11245912 | 0.79 | ABCG2 (0.53) | GBA1NR2F2GALR3EGFRRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4323680-A | 4-Aminoquinazoline compounds useful as agricultural fungicides | SANKYO COMPANY LIMITED (JP) | 1982-04-06 | — | — | US | disclosed |
| US-4213987-A | 4-AMINOQUINAZOLINES | SANKYO COMPANY LIMITED (JP) | 1980-07-22 | — | — | US | disclosed |